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Discovery of Small-Molecule Modulators of Protein–RNA Interactions for Treating Cancer and COVID-19
This book describes the development of novel protein–RNA-binding assays and their applications in a high-throughput manner for the identification of small-molecule modulators of protein–RNA interactions to treat cancer and COVID-19. Modulating protein–RNA interactions with small molecules is expected to provide novel biological insights of the interrelation of diseases with the protein–RNA interactome. The modulations may also be exploited therapeutically. For these reasons, the development of a simple, reliable, and sensitive protein–RNA-binding assay is necessary for high-throughput screening to discover new effective chemical entities capable of acting on diverse protein–RNA interactions. This book discusses the discovery of small-molecule modulators targeting protein–RNA interactions that are potentially valuable to treat cancer and COVID-19 by constructing novel high-throughput screening methods. The results of this dissertation provide valuable insights into the regulation of protein–RNA interactions in chemical biology and drug development.
Fungal Biotechnology for Biofuel Production
Mycology: Current and Future Developments is a book series that brings together the latest contributions to research on the biology, genetics, and industrial use of fungi. Each book chapter is written by academic / professional experts from around the world. The book series is of interest to mycologists and allied researchers seeking to gain new knowledge perspectives about fungi. This volume of the book series focuses chiefly on advances biofuel production. Topics covered in this volume include an overview of biofuel production, the use of lignocelluloses in fungal biofuel production, fungal metabolic engineering, biomass pretreatment for biofuel refineries, and more. The volume also contains chapters about research on other fungi such as S. Cerevisiae. The reviews presented in this volume serve as a useful reference for researchers and readers interested in learning about new developments in biofuel production at a time when the need for alternative energy sources is ever increasing.
Glycoscience: Chemistry and Chemical Biology I–III
Glycostructures play a highly diverse and crucial role in a myriad of organisms and systems in biology, physiology, medicine, and bioengineering and technology. Only in recent years have the tools been developed to partly understand the highly complex functions and chemistry behind them. In this set the editors present up-to-date information on glycostructures, their chemistry and chemical biology, in the form of a comprehensive survey. The text is accompanied by over 2000 figures, chemical structures and reaction schemes and more than 9000 references. The accompanying CD-ROM enables, besides text searches, searches for structures, schemes, and other information.
Food Science
A textbook at the forefront of a global movement toward sustainability Food Science, An Ecological Approach presents food science and food preparation in the context of current environmental world conditions. Throughout the text readers will examine the scientific basis of the dietetics profession and thoroughly explore food chemistry, preparation, safety, regulations, and cultural significance. The science of food is discussed within the broader context of the world's food supply. Food Science, An Ecological Approach explores the idea of global sustainability and examines the ecological problems that challenge our food supply and raise increasing concerns among consumers. Each chapter sets out clear objectives and integrates helpful sidebars, illustrations and discussion questions to increase concept retention. Chapter summaries and special sections found throughout the text engage students and enhance the learning experience. Additional resources are available online which complement the text.
Synthesis and Characterization of Glycosides
This book contains the best known approaches for preparing the main types of glycosides in a short and comprehensive study. It also includes synthetic pathways of challenging glycosides known as antiviral or antineoplasic drugs, or synthetic substrates used for enzymatic detection including those used as substrates for detection of gene markers in plant biotechnology. Special attention is made on the structural characterization, providing the basic tools for the structural assignment through NMR, X-Ray and mass spectra techniques. Some of the chapters cover strategies for preparation of antiviral and antineoplasic drugs included in a drug design course.
The Maillard Reaction
It is almost 100 years since the Maillard reaction was first described. Despite decades of research since then, the products of the reaction and the mechanistic pathways leading to their formation are only gradually being unravelled. Combining comprehensive information regarding the various methods that can be employed in the analysis of Maillard products with a discussion of the advantages and limitations of those methods, this unique book provides a 'one-stop' text from which methods of analysis may be obtained. It will be useful for both new and experienced researchers who are involved in solving the mysteries and complexities of Maillard chemistry.
Paper-based Diagnostics
This book explores the status of paper-based diagnostic solutions, or Microfluidics 2.0. The contributors explore: how paper-based tests can be widely distributed and utilized by semi-skilled personnel; how close to commercial applications the technology has become, and what is still required to make paper-based diagnostics the game-changer it can be. The technology is examined through the lens of the World Health Organization’s ASSURED criteria for low-resource countries (Affordable, Sensitive, Specific, User-friendly, Rapid and robust, Equipment-free, and Deliverable to end-users). Its applications have to include: health technology, environmental technology, food safety, and more. This ...
MCAT Biochemistry Review 2025-2026
Kaplan’s MCAT Biochemistry Review 2025-2026 offers an expert study plan, detailed subject review, and hundreds of online and in-book practice questions—all authored by the experts behind Kaplan's score-raising MCAT prep course. Prepping for the MCAT is a true challenge. Kaplan can be your partner along the way—offering guidance on where to focus your efforts and how to organize your review. This book has been updated to match the AAMC’s guidelines precisely—no more worrying about whether your MCAT review is comprehensive! The Most Practice More than 350 questions in the book and access to even more online—more practice than any other MCAT biochemistry book on the market. The Best...
Stereochemistry and Stereoselective Synthesis
Dieses Lehrbuch aus der Feder anerkannter und erfahrener Autoren füllt ein Lücke. Endlich steht eine prägnante Einführung in Schlüsselkonzepte der organischen Stereochemie und in wichtige klassische sowie moderne Methoden der stereoselektiven Synthese zur Verfügung. Die Konzepte sind reichhaltig in Farbe illustriert. Praktische Beispiel sowie Frage-/Antwortabschnitte tragen zur Festigung der Lehrstoffes bei. Über die Wiley-Website sind Animationen verfügbar. Dieses Buch ist ein Muss für Studenten der Chemie, Biochemie und Biowissenschaften, für Forscher in Pharmaunternehmen und Firmen der Agrochemie, die eine schnelle Einführung in das Fachgebiet suchen.
