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Selected Topics in Exercise Cardiology and Rehabilitation
In this book the lectures of the first course of the International School of Cardiology at Ettore Majorana are presented. It is difficult to reflect in a publication of this kind the atmosphere and spirit of this postgraduate course. Moreover, the beautiful scenery of Erice and its surroundings, celebrated by ancient Greek poets, can never be described by the editors of this book. The purpo~e of this course was to deepen our knowledge accumulated todate on the subjects of non-invasive cardio circulatory assessment and the analysis of the comprehensive approach to cardiac rehabilitation. The clinical value of exercise testing, echo-cardiography, scintigraphy, systolic time intervals have been discussed, as well as the tasks of exercise training, surgery and drugs in the secondary prevention of coronary heart disease. The problems of arrhythmias and the prevention of sudden death have been touched on, as well as early m~bilization after myocardial infarction, the use of digoxin and beta blockers and finally, the controversies in cardiac rehabilitation.
Computerized Cardiopulmonary Exercise Testing
The measurement of cardio-circulatory and gas-exchange parameters during phy sical exercise - the so-called ergo spirometry or cardiopulmonary exercise testing (CPX) - as a basis of pathophysiological and clinical research has a long tradition in Cologne. Knipping and his coworkers, especially Hollmann, performed basic re search work in healthy subjects. In the area of sports medicine, bicycle or treadmill exercise testing with parallel serial lactate determinations has gained increasing im portance for the assessment of cardiac functional capacity. Also, in other medical disciplines, ergospirometry lost its importance. K. Wasserman in Los Angeles is to be credited for having further improve...
Current Catalog
First multi-year cumulation covers six years: 1965-70.
Occult Atherosclerotic Disease
Occult atherosclerotic diseases impose great challenges in the cardiovascular practice. Although their pathology is not much different from that of the overt group of diseases, the clinical approach to their diagnoses remains a puzzle. This has mainly emerged as a result of the problems faced in trying to pick up the vulnerable subjects from among the general public. More definitive candidates to be evaluated are those belonging to one of the high risk groups. There are no statistical figures available on the incidence of occult atherosclerotic disease in the "non risky" general public and this is definitely an area that needs further investigation. Atherosclerotic disease whether they are i...
Anesthesia and Cardiovascular Disease
Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Volume 31 deals with the mechanisms of anesthetic actions under normal conditions as well as pathophysiologic states.Covers anesthetics and cardiac functionAddresses disorders of the cardiovascular system and associated diseasesExplains therapeutic and pathophysiological implicationsDetails reflex regulation of peripheral circulationIncludes full descriptions of the latest methodologiesWritten by internationally recognized experts in the field of anesthesia research
Silent Ischemia
"Silent Ischemia, Current Concepts and Management" contains the proceedings of a conference held in Rottach-Egern, West Germany, March 5 to 7, 1987. We are most grateful to the authors for the effort to provide manuscripts before the meeting, to the sponsor, Bayer AG, for their generous support and to the publishers for their efficient collaboration, all of which have made the appearance of this book possible. When discussing silent myocardial ischemia, the first question is: "why is it silent?". To approach this question, a deeper look has to be taken into the pathophysiology of cardiac pain and the excitatory and inhibitory mechanisms involved. It has to be borne in mind that - in contradiction to what the poets have told us so beautifully for many centuries - the heart is a visceral and not a sensitive organ. If asymptomatic ischemia did not carry prognostic significance comparable to the symp tomatic manifestations of ischemia, then the problem of silent ischemia would be very academic and without consequences for treatment. Therefore studies on prognosis of silent ischemia are of great importance, as their results should indicate how aggressively patients are to be managed.
Inflammation, Lifestyle and Chronic Diseases
Oxidative stress and inflammation are among the most important factors of disease. Chronic infections, obesity, alcohol and tobacco usage, radiation, environmental pollutants, and high-calorie diets have been recognized as major risk factors for a variety of chronic diseases from cancer to metabolic diseases. All these risk factors are linked to ch
Return to Work After Coronary Artery Bypass Surgery
When I gave a presentation on return to work after heart valve replacement at the Tenth Congress of the German Society for Thoracic and Cardiovascular Surgery in 1981, I was surprised by the relatively low level of interest that cardiac surgeons seemed to have in this subject. This stimulated me to intensify my research in this area and to extend it to patients with coron ary heart disease. Obviously, physiological and mechanical aspects of medical treatment are of special interest to the surgeon. For the majority of cardiac surgical patients, that is those with coronary heart disease, the technical problems of the operative procedure have been solved to a great extent. Many studies have demonstrated that, aside from reduction of symptoms, aortocoronary bypass operation can lead to improvement of cardiac performance un der stress conditions. However in spite of the technical solutions to hemodynamic problems, it has become very clear that the reintegration of patients into their social sphere has not been accomplished to the extent that might be expected, as exempli fied by the relatively low rate of postoperative return to work.
Muscle Metabolism During Exercise
Howard G. Knuttgen of Biology, Boston University, 2 Cummington Department Street, Boston, 02215 Massachusetts, USA The relationship of the formation of lactate acid to skeletal muscle energy release in exercising humans was first explored by A. V. Hill and co-workers (2l, 22). The term "oxygen debt" was suggested by them to describe the excess oxygen consumption of recovery which they felt was closely related. A combination of their work and the earlier work of Krogh and Lindhard (35) re sulted at that time in the belief that a certain amount of energy release during the transition from rest to exercise was provided by a non-aerobic source, glycolysis. The resulting accumulation of lactic ac...
