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Adoptive Immunotherapy
An authoritative collection of optimal techniques for producing and characterizing the immunologically active cells and effector molecules now gaining wide use in the clinical treatment of patients. Taking advantage of the latest technologies, the authors present readily reproducible experimental protocols for the study of dendritic cells, T cells, monoclonal antibodies, and bone marrow transplantation. The emphasis is on preclinicical and clinical applications and on the progress of selected approaches in clinical trials. Additional chapters cover the molecular definition of target antigens, mathematical modeling approaches to immunotherapy, and the utilization of regulatory T cells. The protocols make it possible to study the adoptive transfer of tailored antigen-specific immune cells and to improve the clinical application of adoptive immunotherapy.
Stellar Engineering
In terms of the scale of the galaxy, both in space and time, we humans are new comers. Though we are newly on the scene, we are already thinking about how to create large structures in space. Recently, analysis of data from one of the stars in the Kepler data set has led to speculation regarding huge artificial structures (called Stapledon/Dyson Spheres) constructed by advanced extraterrestrial civilizations. The NASA Kepler space observatory has been observing light curves of about 100,000 stars in the constellations of Cygnus and Lyre. This star, popularly dubbed “Tabby’s Star” after the first name of the astronomer leading one of the data reduction teams, shows intriguing periodic d...
Transiting Planets (IAU S253)
The discovery of planets around stars other than the Sun within the past 15 years has opened up one of the largest and most exciting new fields in modern astronomy. The transit method of detecting exoplanets has revealed more information about individual planets than any other method of detection. This volume, the proceedings of IAU Symposium 253, contains a description of the latest development in the field of transiting extrasolar planets. Topical reviews and short contributions from more than one hundred authors present the latest results in the field, from the photometric transit searches for transiting planets, through observational studies of these planets, to the consequences for theories of planet formation, evolution and planetary atmospheres. Presenting the latest research, it is an important resource for graduate students and researchers working in astronomy and planetary sciences.
Star-Planet Interactions
The exoplanet revolution that began three decades ago has drastically changed our knowledge of the extra-solar systems. Today, we face an extreme diversity and complexity of these systems that can only be understood through the intimate link that exists between the planets and their host stars. The understanding, characterization, and the detection of the exoplanets has to be made in close collaboration between stellar and planetary physicists. The purpose of the school and this book is to provide an update of our current knowledge in some selected research fields dedicated to the interplay between stars and planets. It aims to prepare scientists for a rich new decade for exoplanets with space missions like the upcoming PLATO and ARIEL and the new instruments on the VLT and the future ELT.
Bone Marrow Purging and Processing
This volume assesses research findings as well as the clinical aspects now in use for selectively separating subpopulations of cells from bone marrow. It examines a full range of purging processes including transplantation programs, cryopreservation, cell isolation and cell growth, specificity testing and quality control, as well as the development of alternative sources of stem cells, including peripheral blood and cadaveric marrow. It also presents the conditions necessary to optimize graft toxicity and bone marrow transportation and addresses newer techniques of gene probing/processing as well as mechanisms of genetic alteration including electroporation.
Current Catalog
First multi-year cumulation covers six years: 1965-70.
