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STM and SFM in Biology is a book fully dedicated to biological applications of the new technology of scanning probe microscopy (SX). The scanning tunneling microscope (STM) and its first off-spring, the scanning force microscope (SFM), resolve surface topography at the atomic scale. They also detect certain electronic and mechanical properties, and perform well in ultrahigh vacuum, ambient atmosphere, and aqueous solution environments. Thus, STM and SFM offer powerful tools for biological investigations of nucleic acids, proteins, membranes, and living cells. - Introduces the reader to SXM - Presents fundamentals of STM, SFM, and other SXMs - Covers biological applications of STM and SFM - Describes experimental techniques that can be reproduced in the laboratory - Contains extended bibliographies that guide the reader to detailed source publications
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Describes experimental methods for investigating the function of pumps, channels and transporters Covers new emerging analytical methods used to study ion transport membrane proteins such as single-molecule spectroscopy Details a wide range of electrophysiological techniques and spectroscopic methods used to analyze the function of ion channels, ion pumps and transporters Covers state-of-the art analytical methods to study ion pumps, channels, and transporters, and where analytical chemistry can make further contributions
This unique volume provides an integrated overview of the subject of monovalent cations, specifically aimed at students and researchers. It is divided into two parts: the first deals with the processes by which monovalent cations are transported across biological membranes; the second deals with the processes that are affected by changes in intracellular cations. Each chapter describes in simple biochemical terms the interaction between one or more monovalent cations and a particular biological system of importance to current understanding of body function in health and disease. This useful publication is invaluable to students and researchers in biochemistry, physiology, neurology, pharmacology, anesthesiology, cardio-pulmonology, hematology, laboratory medicine, endocrinology, gastroenterology, internal medicine, psychiatry, urology, biomedical physics and medical nutrition.
This volume provides a comprehensive overview of recent advances in targeting glutamate signaling for the treatment of major psychiatric and neurological disorders. It draws on the latest findings in glutamate neurobiology and offers valuable insights into the application of translational principles in neuroscience drug discovery and development. In each chapter, glutamate as a neurotransmitter, its receptors and transporters, and their interplay with other neurotransmitters and neurotrophic factors, are discussed in the context of a specific, highly prevalent and disabling CNS disease. Most recent and detailed information is provided on Ischemic Stroke, Chronic Stress, Major Depressive Diso...
This book explores the scientific causality of sidereal astrology and discusses the power of astrology with arguments given under five headings - Stars, Rays, Gravity (General Law of Relativity), Humans. The hypothesis presented is that electromagnetic plasma radiations coming from Zodiac constellations may be affecting the neurons of the newborn. Despite the main subjects of this research are science-based, not astrology; the data presented as evidence for the theory have been simplified to reach readers who are not interested in physics and astronomy. Information is presented in a concise, clear and attractive way; all content is written in jargon that covers the topics from the very beginning and explains them in a very simplified way. Therefore, this book can be enjoyable for those who want to learn interesting things about the structure of the universe.