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A practical introduction to the applications, principles, design, and fabrication of biosensors, which are used to measure and analyze clinical medical problems, biotechnology processes, environmental impact, and living tissue. This accessible volume emphasizes accuracy of interpretation and maximizing information yield.
Addiction is a chronic relapsing disorder, which comprises impulsive and compulsive elements. Chronic drug consumption leads to long-term neuroadaptive changes in the brain thus result in an addictive state. However, development of addiction is a complex interaction between genetic, epigenetic and environmental factors. The resulting cellular and molecular changes mediate the transition from controlled drug use to the loss of control over drug-taking and drug-seeking. The human association studies helped us to identify some important genetic factors responsible for the susceptibility to addiction. However, social, environmental circumstances highly influence the development of addiction. Usi...
Autism spectrum disorders (ASDs) are a group of genetically and clinically heterogeneous neurodevelopmental disorders characterized by impaired reciprocal social interactions and communication, and restricted and repetitive patterns of behaviors and interests. Studies in genetics, neurobiology and systems biology are providing insights into the pathogenesis of ASDs. Investigation of neural and synaptic defects in ASDs not only sheds light on the molecular and cellular mechanisms that govern the function of the central nervous system, but may lead to the discovery of potential therapeutic targets for autism and other cognitive disorders. Our Research Topic which constitutes this e-book documents the recent development and ideas in the study of pathogenesis and treatment of ASDs, with an emphasis on syndromic disorders such as fragile X and Rett syndromes. In addition, model systems and methodological approaches with translational relevance to autism are covered herein. We hope that the Research Topic will enhance the global knowledge base in the autism research community and foster new research directions in autism related biology.
Bringing together cognitive therapy clinicians, researchers, and theoreticians, this volume integrates the latest findings on the conceptualization and treatment of a range of psychological and psychiatric problems. From depression and anxiety, to eating disorders, hypochondriasis, obsessive-compulsive disorder, panic, personality disorders, sexual problems, social phobia, and substance abuse, authors discuss the needs of individual patients and structuring effective interventions. Factors such as therapist competencey, the theraputic relationship and empathy are systematially examined. Chapters also consider the specific needs of populations such as children and adolescents and the mentally ill.
In Saturn Peach, Lily Wang establishes a distinctive voice that is part heartbreak and part wise witness chronicling the strangeness of a technologized world. When asked to describe her book, Wang answered in her quintessential way, "There are things I never want to know but always know. Every day I live with them. Every day I live. I am like a young fruit. Like a peach, common, not the popular kind but oblate, saturn. I live and inside me this pale fruit, yellow and white. I take bites out of myself and share them with you. Maybe you taste like me. Maybe you hold this fruit and become a tree." If ever there were a book that disarmingly - and seemingly effortlessly - encouraged its reader to become a metaphor, then Saturn Peach is it.
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Addresses adolescent identity issues and suggests practical approaches to facilitate development and adjustment.
Brain disorders, including neurological and neuropsychiatric conditions, represent a challenge for public health systems and society at large. The limited knowledge of their biology hampers the development of diagnostic tools and effective therapeutics. A clear understanding of the mechanisms that underlie the onset and progression of brain disorders is required in order to identify new avenues for therapeutic intervention. Overlapping genetic risk factors across different brain disorders suggest common linkages and pathophysiological mechanisms that underlie brain disorders. Methodological and technological advances are leading to new insights that go beyond traditional hypotheses. Taking a...