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Metabolic Inhibitors V4
Metabolic Inhibitors: A Comprehensive Treatise, Volume IV reviews developments in studies of inhibition of metabolic and enzymic processes ranging from photosynthesis and blood clotting to protein synthesis, fatty acid metabolism, and phospholipid metabolism. The book also explores the inhibition of specific enzyme reactions, such as amino acid activation, amino acid hydroxylation, and cyclic AMP formation. Organized into nine chapters, this volume begins with an overview of allosteric inhibition and inhibitors, and then discusses amino acid hydroxylase inhibitors. The reader is also introduced to inhibitors and activators of enzymes that regulate the cellular concentration of cyclic AMP. In particular, the book describes the role of lipids in the activation of adenyl cyclase by hormones; modification of adenyl cyclase in various physiological and pathological conditions; and synthesis of glycerophosphatides as well as phospho- and glycosphingolipids. This book is a valuable source of information for biochemists and medical research workers as well as virologists, microbiologists, plant physiologists, and agronomists.
Blood
Physiological Pharmacology, Volume V: Blood describes the interrelationships between pharmacology and blood. This volume is organized into five parts encompassing 16 chapters that consider the effect of therapeutic agents on the physiology of blood, whether it be coagulation, the white cells, red cells, or platelets. The opening part deals first with the physiology of blood coagulation and the mode of action of anticoagulants. This part also covers the mechanism of thrombogenesis and thrombolysis, as well as the in vivo actions of thrombolytic agents. The subsequent parts initially examine the biochemistry and physiology of platelets, hematopoietic stem cells, and white cells. These topics a...
Synthetic Substrates in Clinical Blood Coagulation Assays
This book contains the proceedings of a symposium on the use of synthetic substrates in clinical blood coagulation assays, which was held at the University of Leuven, Belgium, on March 1st, 1980. This meeting was organized in order to exchange and discuss recent develop ments and applications in this field. Advantages and disadvantages of synthetic substrates are discussed, while expert workers report on their practical experience with the use of chromogenic substrates in routine assays for blood coagulation and fibrinolysis. The indications when to perform antithrombin III, a2-antiplasmin, factor X and factor II determinations are discussed. For each of the determinations a critical evaluat...
Basic Aspects of Blood Trauma
The contact between the human blood and foreign technical apparatus (circulatory) and respiratory assist devices, arti ficial kidneys) leads to changes in the plasmatic and cel lular components of the blood, which have often only been taken as signs of gross but passive blood destruction. There is much evidence to support this notion in parts (mechanical cellolysis of erythrocytes and thrombocytes), however, these changes have to be seen in a broader bio logical context as an organ-specific reaction of the blood. It is an unjustified oversimplification to simply treat the blood as transport organ for respiratory gases (02 and CO ) and metabolites. The blood is rather also an organ 2 system f...
Laboratory Techniques in Thrombosis — a Manual
The first edition of this manual appeared in 1992 and was entitled ECAT Assay Procedures. It was the result of a unique cooperation between experts brought together by the European Concerted Action on Thrombosis and Disabilities (ECAT). The Concerted Action was at that time under the auspices of the Commission of the European Union. The second edition, like the first edition, deals with diagnostic tests within the field of thrombosis. However, the second edition has a broader scope because it is no longer limited by the frontiers of ECAT. Experts allover the world, in and outside ECAT, have contributed to this edition. The editors are very grateful for their contributions. The need for a new...
Trends in Biomathematics: Mathematical Modeling for Health, Harvesting, and Population Dynamics
This volume offers a collection of carefully selected, peer-reviewed papers presented at the BIOMAT 2018 International Symposium, which was held at the University Hassan II, Morocco, from October 29th to November 2nd, 2018. The topics covered include applications of mathematical modeling in hepatitis B, HIV and Chikungunya infections; tumor cell dynamics; inflammatory processes; chemotherapeutic drug effects; and population dynamics. Also discussing the application of techniques like the generalized stochastic Milevsky-Promislov model, numerical simulations and convergence of discrete and continuous models, it is an invaluable resource on interdisciplinary research in mathematical biology fo...
Phospholipid-Binding Antibodies
First published in 1991. Historically, phospholipid binding antibodies were important in the study of syphilis. During the 1980s there was a resurgence of new interest in these antibodies due to reported associations with recurrent thrombosis, fetal loss, and other clinical disorders. Because of the variety of reported clinical associations and their occurrence in systemic autoimmune disorders, these antibodies have become important in many medical fields, such as clinical immunology, rheumatology, hematology, and obstetrics and gynecology. Phospholipid-Binding Antibodies provides in-depth reviews by specialists in these clinical areas and covers topics including the biochemistry of phospholipids, their role in coagulation, phospholipid immunology, and lupus anticoagulant and antiphospholipid antibodies by solid phase immunoassays. Other topics include thrombosis and fetal loss, as well as the role of phospholipid binding antibodies in these disorders. Antiphospholipid Syndrome and its reported clinical associations is also discussed.
National Library of Medicine Current Catalog
First multi-year cumulation covers six years: 1965-70.
