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Deep beneath the sea off the cold Irish coast, Gaia is a young mermaid who dreams of being human... but at what terrible price? Hans Christian Andersen's dark original fairy tale is reimagined through a searing feminist lens, with the stunning, scalpel-sharp writing and world building that has won Louise her legions of devoted fans.
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Tissue-specific stem cells have the capacity to self-renew and differentiate into several types of functional cells that replenish lost cells throughout an organism?s lifetime. Studies on stem cells from diverse systems have shown that stem cell function is controlled by extracellular cues from the niche and by intrinsic genetic programs within the stem cell. The objectives of this book would be to review the molecular mechanisms that mediate the balanced response of stem cells to the needs of the organisms. Likewise, niches have also been linked to pathologies, by imposing aberrant function on stem cells or other targets. Therefore, the second objective of this book would be to highligh the molecular dysregulation of niche biology leading to the disease. The third objective would be to review the therapeutical targets described within stem cell niches.
A. S. Neill was arguably the most famous child educator of the twentieth century. He was certainly the most controversial. All over the world, countless parents and teachers have been shocked, delighted or inspired by his subversive ideas about education, or by a visit to ‘that dreadful school’ which continues to this day – Summerhill. First published in 1983, this sympathetic but critical exploration of his iconoclastic ideas and personality is the result of interviews with two hundred ex-pupils, parents and teachers about life at Summerhill, and of the practicality of Neill’s philosophy about child freedom. Jonathan Croall has also drawn on many unpublished letters and documents, which help to illuminate Neill’s personal struggles, and his analysis and friendship with Homer Lane, Wilhelm Stekel and Wilhelm Reich. The result is a fascinating and revealing portrait of a remarkable man who, in his absolute determination to be ‘on the side of the child’, remained in permanent opposition to the adult world.