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- Remembering African Wild Dogs is the stunning sixth book in the Remembering Wildlife charity series - The aim of the creators is to make the most beautiful photographic book ever seen on a species and to use that to raise awareness of the plight facing that animal and also funds to protect it - Remembering African Wild Dogs is full of images generously donated by many of the world's top wildlife photographers - All profits from the sale of this book will be donated to projects working to protect wild dogs in Africa - over $1 million USD has been raised by the series so farRemembering African Wild Dogs is the sixth book in the Remembering Wildlife fundraising series, which has so far raised...
Fragment-based drug discovery is a rapidly evolving area of research, which has recently seen new applications in areas such as epigenetics, GPCRs and the identification of novel allosteric binding pockets. The first fragment-derived drug was recently approved for the treatment of melanoma. It is hoped that this approval is just the beginning of the many drugs yet to be discovered using this fascinating technique. This book is written from a Chemist's perspective and comprehensively assesses the impact of fragment-based drug discovery on a wide variety of areas of medicinal chemistry. It will prove to be an invaluable resource for medicinal chemists working in academia and industry, as well as anyone interested in novel drug discovery techniques.
Some of the more recent efforts in tuberculosis (TB) and trypanosomiasis drug discovery from both Product Development Partnerships (PDPs) and academia are highlighted in this this volume. Drug discovery approaches include both target- and phenotypic whole cell screening- approaches. Regarding the latter, mechanism of action studies through target identification are also illustrated.
This book covers intentional design aspects for combinations of drugs, single-molecule hybrids with potential or actual multiple actions, pro-drugs which could yield multiple activity outcomes, and future possibilities. The approach of the book is interdisciplinary, and it provides greater understanding of the complex interplay of factors involved in the medicinal chemistry design and laboratory development of multiply active antibacterials. The scope of the book appeals to readers who are researching in the field of antibacterials using the approach of medicinal chemistry design and drug development.
This is a book of vivid images woven together to bring us the true story of the rainbow nation as it strives to follow Madiba's legacy and face the challenges of the next stage on its long journey.
This nature book reveals the diversity of landscapes and life for which the remarkable eight biomes of the southern African sub-continent are renowned. The introduction to each chapter is a short summary of the main factors that determine the nature of each biome. Then follows a list of places for the traveller where the specific biome is evident.
A look at the research methods in development across the global South Social science researchers in the global South, and in South Africa particularly, utilise research methods in innovative ways in order to respond to contexts characterised by diversity, racial and political tensions, socioeconomic disparities and gender inequalities. These methods often remain undocumented – a gap that this book starts to address. Written by experts from various methodological fields, Transforming Research Methods in the Social Sciences is a comprehensive collation of original essays and cutting-edge research that demonstrates the variety of novel techniques and research methods available to researchers ...