Welcome to our book review site go-pdf.online!
You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
Fragment-Based Drug Discovery
Fragment-based drug discovery is a rapidly evolving area of research, which has recently seen new applications in areas such as epigenetics, GPCRs and the identification of novel allosteric binding pockets. The first fragment-derived drug was recently approved for the treatment of melanoma. It is hoped that this approval is just the beginning of the many drugs yet to be discovered using this fascinating technique. This book is written from a Chemist's perspective and comprehensively assesses the impact of fragment-based drug discovery on a wide variety of areas of medicinal chemistry. It will prove to be an invaluable resource for medicinal chemists working in academia and industry, as well as anyone interested in novel drug discovery techniques.
Fragment-based Approaches in Drug Discovery
This first systematic summary of the impact of fragment-based approaches on the drug development process provides essential information that was previously unavailable. Adopting a practice-oriented approach, this represents a book by professionals for professionals, tailor-made for drug developers in the pharma and biotech sector who need to keep up-to-date on the latest technologies and strategies in pharmaceutical ligand design. The book is clearly divided into three sections on ligand design, spectroscopic techniques, and screening and drug discovery, backed by numerous case studies.
Medicinal Chemistry Approaches to Tuberculosis and Trypanosomiasis
Some of the more recent efforts in tuberculosis (TB) and trypanosomiasis drug discovery from both Product Development Partnerships (PDPs) and academia are highlighted in this this volume. Drug discovery approaches include both target- and phenotypic whole cell screening- approaches. Regarding the latter, mechanism of action studies through target identification are also illustrated.
Transforming Research Methods in the Social Sciences
A look at the research methods in development across the global South Social science researchers in the global South, and in South Africa particularly, utilise research methods in innovative ways in order to respond to contexts characterised by diversity, racial and political tensions, socioeconomic disparities and gender inequalities. These methods often remain undocumented – a gap that this book starts to address. Written by experts from various methodological fields, Transforming Research Methods in the Social Sciences is a comprehensive collation of original essays and cutting-edge research that demonstrates the variety of novel techniques and research methods available to researchers ...
Multiple Action-Based Design Approaches to Antibacterials
This book covers intentional design aspects for combinations of drugs, single-molecule hybrids with potential or actual multiple actions, pro-drugs which could yield multiple activity outcomes, and future possibilities. The approach of the book is interdisciplinary, and it provides greater understanding of the complex interplay of factors involved in the medicinal chemistry design and laboratory development of multiply active antibacterials. The scope of the book appeals to readers who are researching in the field of antibacterials using the approach of medicinal chemistry design and drug development.
Wimbledon Singles Championships - Complete Open Era Results 2014 Edition
This book contains every result at the Wimbledon Gentlemen's and Ladies Singles Championships since the open era began in 1968. For the 2014 edition, there are full details of all 256 players taking part in the main draws, their rankings before and after the tournament and their 5-year performance at Wimbledon. Results from the Roehampton qualifying competition are also included. The statistics section contains a point-by-point record of the finals as well as statistics for the matches and set by set. This 323-page book is a complete record of the 2014 tournament, and a fully detailed reference of the open era at Wimbledon.
Wimbledon Singles Championships - Complete Open Era Results 2015 Edition
This book contains every result at the Wimbledon Men's and Ladies' Singles Championships since the open era began in 1968. For the 2015 edition, there are full details of all 256 players taking part in the main draws, their rankings before and after the tournament and their 5-year performance at Wimbledon. Results from the Roehampton qualifying competition are also included. The statistics section contains a point-by-point record of the finals as well as statistics for the matches and set by set. This 329-page book is a complete record of the 2015 tournament, and a fully detailed reference of the open era at Wimbledon.
