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Novel Diagnostic and Therapeutic Strategies in the Management of Cerebral Gliomas
Cerebral gliomas account for 45% of all primary central nervous system (CNS) tumors. The median survival after the initial diagnosis of glioblastoma (GBM) is only 15 months, and less than 10% of patients survive three years post-diagnosis. Surgical treatment followed by adjuvant therapies such as radiotherapy and chemotherapy represents the classical strategy in glioma management. The revised WHO 2016 classification now distinguishes the oligodendrogliomas with 1p19q codeletion and IDH mutation from the astrocytomas with or without IDH mutations, thereby creating homogenous and pathologically distinct subgroups. While the status of gene expression and mutations define components of GBM subtypes, it was also found that response to therapies was different for each subtype, suggesting that personalized treatment based on genomic alterations could lead to a more favorable outcome for this disease.
Pheochromocytoma (PHEO) and Paraganglioma (PGL)
This book outlines some new advances in genetics, clinical evaluation, localization, therapy (newly including immunotherapy) of pheochromocytoma and paraganglioma including their metastatic counterparts. Well-known and experienced clinicians and scientists contributed to this book to include some novel approaches to these tumors. This book will serve to various health care professionals from different subspecialties, but mainly oncologists, endocrinologists, endocrine surgeons, pediatricians, and radiologists. This book shows that the field of pheochromocytoma/paraganglioma is evolving and a significant progress has been made in last 5 years requiring that health care professionals and scientists will learns new information and implement it in their clinical practice or scientific work, respectively. This book should not be missed by anybody who is focusing on neuroendocrine tumors, their newest evaluation and treatment.
The Role of Toll-like Receptors and their Related Signaling Pathways in Viral Infection and Inflammation
Toll-like receptors (TLRs) represent a powerful system for recognition and elimination of pathogen-associated molecular patterns (PAMPs) from bacteria, viruses, and other pathogens and damage-associated molecular patterns (DAMPs) released from dying cells. TLRs are mainly expressed on immune cells, but can also be present on other cell populations. Typical PAMPs include bacterial cell wall components, viral pathogens, or pathogenic nucleic acids, including viral RNA and DNA. Activation of TLRs leads to the production of proinflammatory cytokines and type I interferons which are important for induction of the host immune response against bacterial and viral infections. However, dysregulation and overstimulation can be detrimental leading to hyper-inflammation, sepsis, and loss of tissue integrity. Furthermore, TLRs are involved in the pathogenesis of acute viral infections, including COVID-19. Consequently, TLRs are promising targets for pharmacological intervention and treatment.
Advanced Intelligent Computing Theories and Applications
This book - in conjunction with the double volume LNCS 9225-9226 - constitutes the refereed proceedings of the 11th International Conference on Intelligent Computing, ICIC 2015, held in Fuzhou, China, in August 2015. The total of 191 full and 42 short papers presented in the three ICIC 2015 volumes was carefully reviewed and selected from 671 submissions. Original contributions related to this theme were especially solicited, including theories, methodologies, and applications in science and technology. This year, the conference concentrated mainly on machine learning theory and methods, soft computing, image processing and computer vision, knowledge discovery and data mining, natural language processing and computational linguistics, intelligent control and automation, intelligent communication networks and web applications, bioinformatics theory and methods, healthcare and medical methods, and information security.
Intelligent Computing Theories and Methodologies
This two-volume set LNCS 9225 and LNCS 9226 constitutes - in conjunction with the volume LNAI 9227 - the refereed proceedings of the 11th International Conference on Intelligent Computing, ICIC 2015, held in Fuzhou, China, in August 2015. The total of 191 full and 42 short papers presented in the three ICIC 2015 volumes was carefully reviewed and selected from 671 submissions. The papers are organized in topical sections such as evolutionary computation and learning; compressed sensing, sparse coding and social computing; neural networks, nature inspired computing and optimization; pattern recognition and signal processing; image processing; biomedical informatics theory and methods; differe...
Future Communication, Computing, Control and Management
This volume contains revised and extended research articles written by prominent researchers participating in the ICF4C 2011 conference. 2011 International Conference on Future Communication, Computing, Control and Management (ICF4C 2011) has been held on December 16-17, 2011, Phuket, Thailand. Topics covered include intelligent computing, network management, wireless networks, telecommunication, power engineering, control engineering, Signal and Image Processing, Machine Learning, Control Systems and Applications, The book will offer the states of arts of tremendous advances in Computing, Communication, Control, and Management and also serve as an excellent reference work for researchers and graduate students working on Computing, Communication, Control, and Management Research.
Advanced Materials for Batteries
The rise of renewable energy responds to global warming, necessitating reliable storage like batteries. Though frequent use can affect their lifespan, these have become smaller, simpler, and more adaptable. Recent technological progress has improved batteries' longevity and efficiency, with costs dropping due to mass production. This book examines different battery types, their evolution, and the cutting-edge materials enhancing their performance, particularly focusing on metal oxides in various battery technologies. Exploring advanced materials for batteries is not just a theoretical exercise but a practical journey into the future of energy. This book is an essential guide, tracing the evo...
Business, Economics, Financial Sciences, and Management
A series of papers on business, economics, and financial sciences, management selected from International Conference on Business, Economics, and Financial Sciences, Management are included in this volume. Management in all business and organizational activities is the act of getting people together to accomplish desired goals and objectives using available resources efficiently and effectively. Management comprises planning, organizing, staffing, leading or directing, and controlling an organization (a group of one or more people or entities) or effort for the purpose of accomplishing a goal. Resourcing encompasses the deployment and manipulation of human resources, financial resources, technological resources and natural resources. The proceedings of BEFM2011 focuses on the various aspects of advances in Business, Economics, and Financial Sciences, Management and provides a chance for academic and industry professionals to discuss recent progress in the area of Business, Economics, and Financial Sciences, Management. It is hoped that the present book will be useful to experts and professors, both specialists and graduate students in the related fields.
Data Processing Techniques and Applications for Cyber-Physical Systems (DPTA 2019)
This book covers cutting-edge and advanced research on data processing techniques and applications for Cyber-Physical Systems. Gathering the proceedings of the International Conference on Data Processing Techniques and Applications for Cyber-Physical Systems (DPTA 2019), held in Shanghai, China on November 15–16, 2019, it examines a wide range of topics, including: distributed processing for sensor data in CPS networks; approximate reasoning and pattern recognition for CPS networks; data platforms for efficient integration with CPS networks; and data security and privacy in CPS networks. Outlining promising future research directions, the book offers a valuable resource for students, researchers and professionals alike, while also providing a useful reference guide for newcomers to the field.
