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Intracranial Stereotactic Radiosurgery
This second edition is written by renowned experts in neurosurgery, neurology, physics, and radiation oncology, many of whom are pioneers of radiosurgery. Throughout more than 30 detailed chapters, the authors share their vast expertise on this highly precise, minimally invasive form of radiation therapy. The first few chapters lay a foundation for understanding the differentiations in types of SRS technology: Leksell Gamma Knife, Novalis, Linac and Proton Beam Radiosurgery, and Cyberknife, followed by an explanation on the physics and radiobiology of SRS. The remaining chapters provide a detailed discussion of all pathologies and disorders currently treated. Highlights: Radiosurgical proced...
Hemorrhagic and Ischemic Stroke
Edited by renowned leaders in the field, Hemorrhagic and Ischemic Stroke: Medical, Imaging, Surgical, and Interventional Approaches provides comprehensive, practical, and cutting-edge information for neurosurgeons, neurologists, radiologists, neurointerventionalists, other health care professionals who care for stroke patients. This go-to reference covers the core of stroke care in a holistic and multidisciplinary approach and will prove essential for physicians and trainees alike. Key Features: The four pillars of stroke care: medical management, imaging, open surgery and neurointerventional surgery, are brought together for the first time, providing a cohesive, strategic methodology for tr...
Tumors of the Central Nervous System, Volume 7
Various aspects, including diagnosis, therapy, and prognosis, of two brain tumors (meningioma and schwannoma) , of brain tumors are discussed in this volume. Insights on the understanding of molecular pathways involved in brain tumor biology are explained. For example, the role of E-cadherin gene instability, carbonic anhydrase 11, urokinase plasminogen activator, and Wnt signaling is discussed in detail. Such information will lead to the development of effective aniicancer drugs. The role of molecular genetics and epigenetic mechanisms in schwannomas is explained. Also, is explained the role of cyclin D1 in vestibular schwannoma. The determination of subtypes of meningiomas using perfusion ...
Intracranial Stereotactic Radiosurgery, An Issue of Neurosurgery Clinics
This issue of the Neurosurgery Clinics of North America devoted to Intracranial Stereotactic Radiosurgery is Guest Edited by Dr. Bruce Pollock of the Mayo Clinic in Rochester, Minnesota. Articles in this issue include: Concepts and Techniques of Intracranial Stereotactic Radiosurgery; Stereotactic Radiosurgery of Intracranial Meningiomas; Stereotactic Radiosurgery of Pituitary Adenomas; Stereotactic Radiosurgery of Vestibular Schwannomas; Stereotactic Radiosurgery of Non-Vestibular Schwannomas; Multi-session Radiosurgery of Benign Intracranial Tumors; Stereotactic Radiosurgery of Intracranial Gliomas; Stereotactic Radiosurgery of Brain Metastases; Stereotactic Radiosurgery of Chordomas, Chondrosarcomas, and Glomus Tumors; Stereotactic Radiosurgery of Intracranial Arteriovenous Malformations; Stereotactic Radiosurgery of Intracranial Dural Arteriovenous Fistulas; Stereotactic Radiosurgery of Intracranial Cavernous Malformations; Stereotactic Radiosurgery for Trigeminal Neuralgia; and Stereotactic Radiosurgery for Epilepsy and Functional Disorders.
Schmidek and Sweet: Operative Neurosurgical Techniques E-Book
Wherever, whenever, or however you need it, unmatched procedural guidance is at your fingertips with the new edition of Schmidek & Sweet: Operative Neurosurgical Techniques! Completely revised under the auspices of new editor-chief Dr. Alfredo Quiñones-Hinojosa, this comprehensive medical reference examines indications, operative techniques, complications, and results for nearly every neurosurgical procedure. Full-color illustrations, 21 new chapters, internationally-acclaimed contributors, surgical videos, and online access make it a "must have" for today's practitioner. Hone your skills for Master virtually every routine and specialized procedure for brain, spinal, and peripheral nerve pr...
Principles and Practice of Stereotactic Radiosurgery
Principles and Practice of Stereotactic Radiosurgery, Second Edition serves as the definitive reference textbook for SRS practitioners. It provides a theoretical basis for the use of therapeutic radiation including imaging techniques and radiobiology. The bulk of the textbook contains chapters that are comprehensive in scope on all diseases that are treated by SRS. Lastly, it addresses administrative and technical aspects of running an SRS unit. Each chapter provides an expansive treatment of the subject, with emphasis placed on the technical aspects of SRS so that practitioners in this field can use it as a daily reference. Written by noted experts in the field, Principles and Practice of Stereotactic Radiosurgery, Second Edition is the only reference needed for neurosurgeons, radiation oncologists and medical physicists at all levels of training and practice who are interested in SRS.
Tumors of the Central Nervous System, Volume 4
This volume mainly contains information on the diagnosis, therapy, and prognosis of brain tumors. Insights on the understanding of molecular pathways involved in tumor biology are explained, which should lead to the development of effective drugs. Information on pathways (e.g., hedgehog) facilitates targeted therapies in cancer. Tumor models are also presented, which utilize expression data, pathway sensitivity, and genetic abnormalities, representing targets in cancer. For example, rat model of malignant brain tumors using implantation of doxorubicin with drug eluting beads for delivery is explained. The future of pathway-driven therapies for tumors is summarized. The importance of personal...
Current and Future Management of Brain Metastasis
Latest guidelines for disease control of brain metastasis Recent strategies combining multiple modalities have opened up a whole new field of brain metastasis management focusing on disease control. The management of brain metastasis in modern times is no longer confined to palliation but seeks preservation of life quality and not only prolonged survival. Up-to-date guidelines and the main aspects of brain metastasis management as well as practical points on how to deal with difficult situations in daily clinical practice are presented. Epidemiology and biology and various effective treatment methods such as surgery, radiosurgery, radiation therapy and chemotherapy are well explained. Each chapter encompasses extensive reviews and presents broad perspectives on specific topics by the most renowned personages who have continuously shown their excellence in this rapidly progressing field. This book contains the most current information on the understanding of brain metastasis management. It is valuable reading for neurosurgeons, neuro-oncologists and radiation oncologists who are searching for the best all-round treatment for their patients.
Cavernous Malformations of the Nervous System
Questions regarding the nature and appropriate management of cavernous malformation (CM) have clouded researchers and those faced with making clinical decisions for several decades. CMs may be seen as an incidental finding on MRI studies, or they may present with symptoms, such as seizures or intracranial hemorrhage, often causing severe neurologic deficit. Cavernous Malformations of the Nervous System provides a comprehensive and authoritative review of the current practice in diagnosis and management of these cerebrovascular disorders. Emphasis has been laid on the understanding of basic sciences with chapters committed to understanding of CCM1, 2 and 3 genes and their role in CCM biology, as well as clinical genetics. Controversial topics which continue to pose treatment challenges such as safety of anticoagulation and prophylactic management during pregnancy are also discussed. This book will be of interest to basic science researchers, neurosurgeons and vascular neurologists both in academic institutions and private practice.
Adult CNS Radiation Oncology
This book elucidates the radiation therapy protocols and procedures for the management of adult patients presenting with primary benign and malignant central nervous system tumors. With the development of new treatment strategies and rapid advancement of radiation technology, it is crucial for radiation oncologists to maintain and refine their knowledge and skills. Dedicated exclusively to adult CNS radiation oncology, this textbook explores CNS tumors ranging from the common to the esoteric as well as secondary cancers of metastatic origin. The first half of the book is organized anatomically: tumors of the brain, spinal cord, leptomeninges, optic pathway, ocular choroid, and skull base. Th...
