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Regulation of Downstream Targets
Regulation of Downstream Targets, Volume 134 in the Advances in Protein Chemistry and Structural Biology series, presents interesting chapters on topics such as Transcriptional regulatory mechanisms and signaling networks in Viral Infections, Identification of potential key genes associated with pathogenesis and prognosis of endometrial cancer based on Integrated Bioinformatics Approaches, Differential regulation of genes in stage IB pancreatic cancer associated with increased risk of metastasis, AMPK-related LKB1-downstream targets, A compilation of bioinformatic approaches to identify novel downstream targets for the detection and prophylaxis of cancer, Protein phosphatases and their targe...
Poly(lactic-co-glycolic acid) (PLGA) Nanoparticles for Drug Delivery
Poly(lactic-co-glycolic acid) (PLGA) Nanoparticles for Drug Delivery is a comprehensive guide to PLGA nanoparticles for targeting various diseases, covering principles, formation, characterization, applications, regulations and the latest advances. Sections introduce the fundamental aspects of PLGA nanoparticles for drug delivery, including properties, preparation methods, characterization, drug loading methods, and drug release mechanisms, along with a focus on applications. Application of PLGA nanoparticles for the treatment of cancer, inflammatory, cerebral, cardiovascular, and infectious diseases, as well as in regenerative medicine, photodynamic and photothermal therapy, and gene therap...
Ethnic Knowledge and Perspectives of Medicinal Plants
This new 2-volume set aims to share and preserve ethnic and traditional knowledge of herbal medicine and treatments, while also emphasizing the link between biodiversity, human nutrition, and food security. Ethnic Knowledge and Perspectives of Medicinal Plants is divided into two volumes, with volume 1 focusing on the traditional use of curative properties and treatment strategies of medicinal plants, and volume 2 addressing the varied nutritional and dietary benefits of medicinal plants and the practice of Ayurveda. Both volumes stress the importance of bioresources for human nutrition and nutraceuticals based on ethnic knowledge and the need for efforts to protect biodiversity in many regi...
Precision Medicine and Human Health
Precision Medicine and Human Health covers several aspects of precision medicine in 20 edited reviews by researchers and healthcare professionals. The breadth of information provided by the contributors aims to familiarize readers with basic and applied research in personalized therapy. Starting with an overview of the subject and its relationship with epigenetics, the book progresses into advanced topics that explain its wider applications. The use of precision medicine in treating different diseases such as protein misfolding disorders, gut ulcers and their effect on the gut microbiome, cancer treatment (for hepatocellular carcinoma, breast cancer, and oral cancer), fibromyalgia, high alti...
Intellectual Property Issues in Life Sciences
Intellectual Property Issues in Life Sciences: Disputes and Controversies highlights emerging legal, social, and regulatory issues pertaining to various areas of life sciences. Patents occupy a prominent position in the innovation systems in the life sciences, but to what extent they support, or hinder innovation is widely disputed. Life science is a broad subject including agriculture, ecology, microbiology, plant and animal sciences, health and diseases, biotechnology, etc. However, despite the broad applications of biotechnology and molecular biology techniques, profits on investments are surprisingly low. Thus, it is vitally important for universities, public research organizations, and ...
Personalized Epigenetics
Personalized Epigenetics, Second Edition discusses the core translatability of epigenetics to health management of individuals who have unique variations in their epigenetic signatures that can guide both disorder and disease prevention and therapy. Fully updated and revised, this new edition details inter-individual variability in the major epigenetic process in humans consisting of DNA methylation, histone modifications, noncoding RNA, and the diagnostic, prognostic, and therapeutic potential of the field. It also reviews the impact of the environment on epigenetic variations among individuals and the role of pharmacology and drug development in personalized epigenetics. Most importantly, ...
Diabetic Foot Ulcer
This book discusses essential aspects of diabetic foot ulcers, including evidence-based information on its pathogenesis and pathophysiology, as well as the molecular mechanisms and biomechanics of the diabetic foot. It also highlights the need for a multidisciplinary team to be involved in the management of diabetic patients with foot ulcers, and describes available and future tools for evaluating patients who are at risk. Exploring the main current therapies as well as the latest developments, future directions and potential new treatments, such as growth factors, stem cell therapy, alternative medicine and nanotechnology, the book is a valuable resource for clinicians and medical graduates but will also appeal to researchers working in the field.
