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Modeling in Systems Biology
The emerging, multi-disciplinary field of systems biology is devoted to the study of the relationships between various parts of a biological system, and computer modeling plays a vital role in the drive to understand the processes of life from an holistic viewpoint. Advancements in experimental technologies in biology and medicine have generated an enormous amount of biological data on the dependencies and interactions of many different molecular cell processes, fueling the development of numerous computational methods for exploring this data. The mathematical formalism of Petri net theory is able to encompass many of these techniques. This essential text/reference presents a comprehensive o...
Computational Systems Biology
This comprehensively revised second edition of Computational Systems Biology discusses the experimental and theoretical foundations of the function of biological systems at the molecular, cellular or organismal level over temporal and spatial scales, as systems biology advances to provide clinical solutions to complex medical problems. In particular the work focuses on the engineering of biological systems and network modeling. - Logical information flow aids understanding of basic building blocks of life through disease phenotypes - Evolved principles gives insight into underlying organizational principles of biological organizations, and systems processes, governing functions such as adaptation or response patterns - Coverage of technical tools and systems helps researchers to understand and resolve specific systems biology problems using advanced computation - Multi-scale modeling on disparate scales aids researchers understanding of dependencies and constraints of spatio-temporal relationships fundamental to biological organization and function.
PRICAI 2000 Topics in Artificial Intelligence
PRICAI 2000, held in Melbourne, Australia, is the sixth Pacific Rim Interna tional Conference on Artificial Intelligence and is the successor to the five earlier PRICAIs held in Nagoya (Japan), Seoul (Korea), Beijing (China), Cairns (Aus tralia) and Singapore in the years 1990, 1992, 1994, 1996 and 1998 respectively. PRICAI is the leading conference in the Pacific Rim region for the presenta tion of research in Artificial Intelligence, including its applications to problems of social and economic importance. The objectives of PRICAI are: To provide a forum for the introduction and discussion of new research results, concepts and technologies; To provide practising engineers with exposure to ...
Petri Nets and Other Models of Concurrency - ICATPN 2006
This book constitutes the refereed proceedings of the 27th International Conference on Applications and Theory of Petri Nets and Other Models of Concurrency, ICATPN 2006, held in Turku, Finland in June 2006. The book presents 16 revised full papers and 6 revised tool papers together with 4 invited papers. All current issues on research and development in the area of Petri nets and modeling of concurrent systems are addressed.
Terror Down Under
In 1948, the Australian government banned the production, importation and exhibition of horror films in a move to appease religious communities and entertainment watchdogs. Drawing upon previously unseen government documents, private letters and contemporary newspaper accounts, this book is the first to extensively cover the history of censorship and the early production of horror movies in Australia. Beginning its examination in the late 19th century, the book documents the earliest horror films like Georges Melies' The Haunted Castle (1896), and how Australians enjoyed such films before the ban. The book then explains how certain imports, like 1954's Creature from the Black Lagoon, were able to circumvent the ban while others were not. It also reveals how Australian television, though similarly impacted by government censorship, was occasionally able to broadcast films technically banned from cinematic release. The work concludes with a look at the first Australian horror films produced after the ban was formally lifted in 1969, like Terry Bourke's Night of Fear (1973).
Systems Biology Modelling and Analysis
Describes important modelling and computational methods for systems biology research to enable practitioners to select and use the most suitable technique Systems Biology Modelling and Analysis provides an overview of state-of-the-art techniques and introduces related tools and practices to formalize models and automate reasoning for systems biology. The authors present and compare the main formal methods used in systems biology for modelling biological networks, including discussion of their advantages, drawbacks, and main applications. Each chapter includes an intuitive presentation of the specific formalism, a brief history of the formalism and of its applications in systems biology, a fo...
Proceedings Of The 3rd Asia-pacific Bioinformatics Conference
High-throughput sequencing and functional genomics technologies have given us a draft human genome sequence and have enabled large-scale genotyping and gene expression profiling of human populations. Databases containing large number of sequences, polymorphisms, and gene expression profiles of normal and diseased tissues in different clinical states are rapidly being generated for human and model organisms. Bioinformatics is thus rapidly growing in importance in the annotation of genomic sequences, in the understanding of the interplay between genes and proteins, in the analysis the genetic variability of species, etc. The 3rd APBC brings together researchers, professionals, and industrial p...
Selected Topics In Post-genome Knowledge Discovery
The Institute for Mathematical Sciences at the National University of Singapore organized a program on “Post-Genome Knowledge Discovery” from January to June 2002. The program focused on the computational and statistical analysis of sequences and genetics, and the mathematical modeling of complex biological interactions, which are critical to the accurate annotation of genomic sequences, the study of the interplay between genes and proteins, and the study of the genetic variability of species. As part of the program, tutorials for graduate students and newcomers to this transdisciplinary area of research were given by experts in these fields.This important volume collects the expanded notes of some of the tutorials that were given during the program. The topics include comparison and alignment of biological sequences, modeling and analysis of biological pathways, data mining and knowledge discovery from biological and clinical data.
