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The Brain and Host Defense
  • Language: en
  • Pages: 362

The Brain and Host Defense

  • Type: Book
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  • Published: 2009-12-24
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  • Publisher: Elsevier

It is now well recognized that the brain, and especially the hypothalamus, plays an important role in the regulation of immune reactions and inflammation. This book aims to review our current state of knowledge of this important field. Key historical findings are presented, and the reciprocal interactions between the brain and the immune system are examined. Particular emphasis is placed on inflammation, a critical host defense reaction that serves as an effector response for both the adaptive and innate immune systems.Mechanisms implicated in brain defense, as well as in more general host defense, are discussed. The regulatory influences of the brain on inflammatory responses are included w...

The Role of Bioactive Lipids in Cancer, Inflammation and Related Diseases
  • Language: en
  • Pages: 256

The Role of Bioactive Lipids in Cancer, Inflammation and Related Diseases

The Organizing Committee of the 15th International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases compiled a group of junior investigators to provide reviews on the topics they presented at the Puerto Vallarta Bioactive Lipids conference, as part of the book series, Advances in Experimental Medicine and Biology (AEMB). The book in this series will be titled Bioactive Lipids in Cancer, Inflammation and Related Diseases. Topics range from all classes of lipids including prostaglandins, resolvins, spingolipids, P450-derived lipids, endocannabanoids and phospholipids. The focus includes physiology, cell biology, and structural studies in organisms from bacteria to humans and how these studies addressed the role of lipids in various disease i.e. cancer, inflammation, diabetes, obesity, cardiovascular disease and others.

Engineered Nanomaterials and Phytonanotechnology: Challenges for Plant Sustainability
  • Language: en
  • Pages: 342

Engineered Nanomaterials and Phytonanotechnology: Challenges for Plant Sustainability

  • Type: Book
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  • Published: 2019-11-20
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  • Publisher: Elsevier

Engineered Nanomaterials and Phytonanotechnology: Challenges for Plant Sustainability, Volume 87 in the Comprehensive Analytical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters on the Environmental application of nanomaterials: A promise to sustainable future, Plant-nanoparticle interactions: Mechanisms, effects, and approaches, A general overview on application of nanoparticles in agriculture and plant science, Engineered nanomaterials uptake, bioaccumulation and toxicity mechanisms in plants, Engineered nanomaterials in plants: Sensors, carriers, and bio-imaging, Antioxidant role of nanoparticles for enhancing ecological performance of plant system, Toxicity assessment of metal oxide nanoparticles on terrestrial plants, and much more.

Chronic Inflammation
  • Language: en
  • Pages: 463

Chronic Inflammation

  • Type: Book
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  • Published: 2012-09-17
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  • Publisher: CRC Press

Although acute inflammation is a healthy physiological response indicative of wound healing, chronic inflammation has been directly implicated in a wide range of degenerative human health disorders encompassing almost all present day non-communicable diseases including autoimmune diseases, obesity, diabetes and atherosclerosis. Chronic Inflammation

The Resolution of Inflammation
  • Language: en
  • Pages: 246

The Resolution of Inflammation

This book provides readers with an up-to-date and comprehensive view on the resolution of inflammation and on new developments in this area, including pro-resolution mediators, apoptosis, macrophage clearance of apoptotic cells, possible novel drug developments.

Lipidomics and Bioactive Lipids: Mass Spectrometry Based Lipid Analysis
  • Language: en
  • Pages: 432

Lipidomics and Bioactive Lipids: Mass Spectrometry Based Lipid Analysis

  • Type: Book
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  • Published: 2007-11-26
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  • Publisher: Elsevier

This volume in the well-established Methods in Enzymology series features methods for the study of lipids using mass spectrometry techniques. Articles in this volume cover topics such as Qualitative Analysis and Quantitative Assessment of Changes in Neutral Glycerol Lipid Molecular Species within Cells; Glycerophospholipid identification and quantitation by electrospray ionization mass spectrometry; Detection and Quantitation of Eicosanoids via High Performance Liquid Chromatography/Electrospray Ionization Mass Spectrometry; Structure-specific, quantitative methods for "lipidomic" analysis of sphingolipids by tandem mass spectrometry; Analysis of Ubiquinones, Dolichols and Dolichol Diphospha...

New Emitters for OLEDs
  • Language: en
  • Pages: 281

New Emitters for OLEDs

Organic light emitting diodes (OLEDs) enable the energy-efficient generation of light, and thus find application for displays or lighting. In particular, luminescent copper(I) complexes present a promising, resource- and cost-efficient class of emitting materials for OLEDs and have attracted enormous interest due to their high emission efficiencies and color tunability by ligand variation. The assessment of thermally activated delayed fluorescence (TADF) to copper(I) compounds has accelerated the development and investigation of several complex classes. Herein, novel emitting materials based on mononuclear neutral copper(I) complexes of the type [(NN)Cu(PP)] have been developed and a deeper ...

Inflammation and Oxidative Stress in Neurological Disorders
  • Language: en
  • Pages: 364

Inflammation and Oxidative Stress in Neurological Disorders

Unless new discoveries are made in the prevention or treatment of stroke, Alzheimer's Disease and depression, the number of patients with these diseases is sure to increase dramatically by the year 2050. Thus, developing strategies to retard or delay the onset of stroke, AD and depression these neurological disorders is of critical important. The present monograph will provide current and comprehensive information on the relationship between neuroinflammation and oxidative stress in age-related neurological disorders at the molecular level. The information described in this monograph on lifestyle (diet and exercise), genes and age is intended to facilitate and promote new discoveries for the treatment of age-related neurological disorders.

Bioactive Lipids in Health and Disease
  • Language: en
  • Pages: 193

Bioactive Lipids in Health and Disease

  • Type: Book
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  • Published: 2019-05-28
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  • Publisher: Springer

The purpose of this book is to introduce the readers on the perspective of the role that unsaturated fatty acids and complex lipids play on health and disease. Bioactive lipids can be modified affecting membrane composition, structure and fluidity in addition to changes in cell signaling associated to lipid-protein (membrane receptors) interactions, issues that are addressed by the authors. This book analyzes key topics involving bioactive lipids and their role in normal signaling and the mechanisms of disease. The book navigates from structural studies of oxidized and non-oxidized lipids to the reactions and cell signaling processes that bioactive lipids play in cardiovascular and neurodege...

Adverse Childhood Experiences and Their Life-Long Impact
  • Language: en
  • Pages: 458

Adverse Childhood Experiences and Their Life-Long Impact

  • Type: Book
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  • Published: 2023-08-08
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  • Publisher: Elsevier

Adverse Childhood Experiences and Their Life-Long Impact explores how these experiences influence cognitive, behavioral and social experiences in adulthood. The book conceptualizes the types of violence, abuse, neglect, and/or trauma that factor into ACEs. It also explores the psychopathological outcomes of ACEs among children, including neurodevelopmental and psychosocial mechanisms. By drawing on cross-cultural perspectives, the authors provide insight into the variations between the adversity and trauma children experience. Sections also cover preventive measures, risk factors and various forms of interventional treatment, making this book a core read for psychologists, physicians, social workers, educators and researchers in the field. - Provides a comprehensive framework for understanding adverse childhood experiences - Reviews the link between ACE and homelessness, substance abuse, and physical and/or sexual violence in adulthood - Highlights key components of cross-cultural perceptions on child abuse and neglect, including differences of gender - Explores options for prevention and intervention for those who experience adverse childhood experiences