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PET/CT holds great promise for the management of many types of infection and inflammation. This issue discusses many of these uses, starting with arthroplasty-associated infection. FDG PET/CT also has utility in inflammatory bowel disease. This issue also discusses the utilization of FDG PET and PET/CT in the evaluation of diabetic foot, and in monitoring therapeutic effect in patients without malignancy. PET/CT is reviewed regarding its use in patients with sarcoidosis or IgG4 disease. Also covered is the application of FDG PET/CT in detecting the source of fever of unknown origin. Artherosclerosis and vasculitis can be assessed by PET/CT and FDG PET/CT can also be used in the management of severe infection in patients with malignancies. Finally, the issue discusses the use of PET and PET/CT in the evaluation of osteomyelitis.
This issue of PET Clinics is Part II of a two-part issue, and focuses on PET-CT-MRI Applications of Musculoskeletal Disorders. It is edited by Drs. Abass Alavi (the Consulting Editor of PET Clinics), Ali Salavati, Ali Gholamrezanezhad and Ali Guermazi. Articles will include:Applications of PET-CT-MR in the management of benign musculoskeletal disorders; Diagnostic management of primary and secondary spinal neoplastic disease: The role of PET-CT-MRI; Skeletal Metastasis Evaluation: Value and impact of PET/CT on Diagnosis, Management and Prognosis; Hybrid imaging (PET CT/PET MRI) of bone metastases; Diffusion-weighted MR Imaging in Evaluating Bone Metastases; Imaging of Osteoarthritis by Conventional Radiography, MRI, PET-CT and PET-MRI; Evolving Role of MRI and PET in Assessing Osteoporosis; Evolving Role of Novel PET-CT-MRI based quantitative technique for Assessing Muscle Disorders; Pediatric musculoskeletal applications of PET-CT-MRI; In vivo molecular imaging of inflammation and infection; Future perspective of the application of PET-CT-MRI in musculoskeletal disorders; and more!
PET imaging has been used for the assessment of lung cancer for several years for diagnosis, staging, and post-treatment follow up. Expanded applications are now being used and explored in the imaging of the heart, thoracic vascular disease, and chest wall disorders. This issue provides an up-to-date review of the uses of PET for oncologic and nononcologic diseases of the thorax.
This issue of PET Clinics focuses on PET Imaging in Pediatric Patients and is edited by Drs. Hongming Zhuang and Abass Alavi. Articles will include: Promising New PET tracers in the evaluation of pediatric disease; F-DOPA PET/CT in the management of congenital hyperinsulinism; Emerging roles of PET/MRI in pediatric hospital; Roles of FDG PET/CT in the management of posttransplant lymphoproliferative disease in pediatric patient; FDG-PET/CT in the management of pediatric lymphoma; Preparation and logistic consideration in performing PET/CT and PET/MRI in pediatric patients; PET/CT in the evaluation of FUO and infectious/inflammatory disease in pediatric patients; Roles of PET/CT in the evaluation of neuroblastoma; Potential Roles of Total Body Imaging in Pediatric Diseases and Disorders; PET/CT in the Management of Pediatric Sarcomas; Pediatric Cardiac PET Imaging; Dosimetry between PET/CT and PET/MRI: Implications in Pediatric Imaging; Essential Role of Global Disease Assessment in Assessing Systemic Disorders, and more!
PET/CT is an integral part of the evaluation of patients who have head and neck cancer. In this issue, the state of the art in PET/CT imaging is discussed. The issue starts with an overview of FDG-PET/CT, PET and MRI for normal anatomy, including pitfalls and artifacts. This topic is followed by a review of FDG-PET/CT for initial and subsequent therapy evaluation; progressing to PET and MRI. Other articles discuss SUV as a prognostic factor in head and neck squamous cell carcinoma, PET in head and neck cancer radiotherapy treatment planning, PET in decision making for neck dissection after radiation treatment, and newer methods for improving yield from FDG-PET imaging for accurate staging, determining tumor biology, and assessing prognosis. The issue focuses on some of the most cutting-edge applications, such as new tracers PET in head and neck squamous cell carcinoma (including FLT and hypoxia imaging). PET scans in thyroid cancer is also discussed.
This issue of PET Clinics focuses on PET-Based Novel Imaging Techniques with Recently Introduced Radiotracers and is edited by Drs. Mona-Elisabeth R. Revheim and Abass Alavi. Articles will include: Prostate-Specific Membrane Antigen PET in Prostate Cancer: 68Ga/18F labelled; Critical Role of FDG in Hormonally Active Malignancies; Role of Amino-Acid Tracers and FDG in the Diagnosis of Brain Tumors; FACBC/Fluciclovine PET Imaging in Prostate Cancer; Somatostatin PET in NEN: DOTA-peptides + 68Ga/64Cu labelled; Imaging of Insulinoma with PET: DOTA-peptides, Exendin-4 PET/CT; Preclinical Evaluation of TSPO and MAO-B PET Radiotracers in an LPS Model of Neuroinflammation; Molecular Imaging of Movement Disorders; Imaging of Cardiac Amyloidosis; and more!
The technique for successfully completing a PET procedure is complex and involves a knowledge of physics, pharmacy, anatomy, physiology, and the disease process; applying PET scanning to children is even more challenging and technically demanding. One cannot simply adopt the approach used for adults but instead must receive specialized training in order to master pediatric PET procedures. This one-of-a-kind, interdisciplinary book is one of the first practical guides to imaging children with PET. The text opens with a section that focuses on practical and technical issues of pediatric PET imaging, including radiation dose and sedation. Principles of operation, instrumentation, and nuclear medicine regulations are also discussed. Subsequent sections cover the clinical applications of PET in pediatrics. With contributions from leading international authorities in the field, each chapter is heavily illustrated and provides the reader with extensive coverage of the essentials of clinical PET studies in oncology and neurology, which standout as key areas for PET imaging in pediatrics.
This issue provides a complete update on PET imaging of lymphoma, starting with a clinical assessment of lymphoma and the role of medical imaging. The role of structural imaging in lymphoma is then discussed. From a Nuclear Medicine perspective, FDG-PET in lymphoma is reviewed, as is the role of FDG-PET in pediatric lymphoma. Next, the role of non-FDG tracers in lymphoma is reviewed. Other articles cover the role of fMRI and optical imaging in lymphoma, the role of diffusion-weighted MRI in lymphoma, FDG-PET in personalization of therapy in patients with lymphoma, and PET and radiation oncology in lymphoma.
This book provides a contemporary reference to the science, technology and clinical applications of PET and PET/CT. The book is designed to be used by residents and fellows training in medical imaging specialties as well as imaging experts in private or academic practice who need to become familiar with this technology and its applications. It is also for use by those whose specialties carry over to PET and PET/CT, referring physicians such as oncologists, cardiologists, neurologists and surgeons. Developed as an offshoot/update of the "clinical practice" portion of the main book, edited by PE Valk et al, published in 2003 (Positron Emission Tomography: basic science and clinical practice), this offshoot covers the second half of the main book only, dealing with mainly the clinical research and practice. Most of the book comprises chapters updated from the "Clinical practice" portion of the main Valk book. It contains 6 brand new chapters and 22 completely revised and updated chapters from the main Valk book.
Imaging of the spine is given a thorough update in this issue, beginning with an article on spine segmentation, enumeration and normal variants. Imaging of degenerative disease of the spine is then reviewed, giving consideration to appropriate utilization of imaging, specificity and sensitivity shortcomings in evaluation of degenerative disease, risks and benefits of imaging of degenerative disease, and the prevalence of radicular and xial pain and underlying pain generators. Next, the validity and socioeconomic impact of spine imaging in evaluating “degenerative pain syndromes is reviewed. Pathophysiology and biomechanics of disc and posterior element of degenerative disease is reviewed, along with imaging of radiculopathy / radiculitis, imaging of central canal stenosis, and imaging of discogenic pain (using MRI and discography). Imaging of joint related axial pain, spine neoplasm, spine infection, and non-acute trauma is also covered.