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During the past several years tremendous advancements have been made in the field of pharmacology and therapeutics. While new therapeutic strategies are coming up, old ones are being improved by modifications, or being replaced with newer ones. The major topics covered in this book include: endothelins, current topics in cardiovascular research, molecular pharmacology, recent developments in cancer research, antioxidants, oxidants and human disease, herbal drugs, developments in neuropharmacology, myelin biology and demyelinating disease, pharmacovigilance, role of cytokines in health and disease, ocular pharmacology, detoxification of xenobiotics-biotransformation and transport, and several other topics of current interest. The aim of this book is to fulfill the needs of the basic and clinical researchers as well as the students, particularly related to areas of current interest in pharmacology and therapeutics.
This book presents the proceedings of the 7th conference Healthcare Systems Ergonomics and Patient Safety (HEPS), held in Delft, The Netherlands on November 2-4, 2022, which was endorsed by the International Ergonomics Association (IEA). Contributions focus on the integration of knowledge, methods, and expertise from the disciplines of Human Factors/Ergonomics and of Medicine and Health in order to contribute to a safe and humane, high-quality healthcare system. Through breaking down the barriers between disciplines, they foster a framework of scientific knowledge, expertise and best practices to create the future of health and healthcare. The proceedings include papers from researchers and practitioners, scientists and physicians, institutional leaders, managers and policy makers that contribute to constructing the Human Factors and Ergonomics approach across a variety of methodologies, domains and productive sectors.
Organophoshorus Chemistry provides a comprehensive and critical review of the recent literature. Coverage includes phosphines and their chalcogenides, phosphonium salts, low coordination number phosphorus compounds, penta- and hexa- coordinated compounds, tervalent phosphorus acid derivatives, quiquevalent phosphorus acids, nucleotides and nucleic aicds, ylides and related compounds, phosphazenes and the application of physical methods in the study of organophosphorus compounds. This Specialist Periodical Report will be of value to research workers in universities, government and industrial research organisations whose work involves the use of organophosphorus compounds. It provides a concise but comprehensive survey of a vast field of study, with a wide variety of applications, enabling the reader to keep abreast of the latest developments in their specialist fields.
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Annual Reports in Medicinal Chemistry: Roadmaps, Volume 62 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. This release provides a compendium of information on newly approved drugs and compounds entering late-stage clinical trials, making it a valuable resource for graduate students pursuing research in medicinal chemistry - Reviews on hot topics of interest in small molecule drug discovery heavily pursued by industrial research organizations - Provides preclinical information in the context of chemical structures - Includes section editors who are highly knowledgeable and who can evaluate invited reviews for scientific rigor
Progress in Heterocyclic Chemistry (PHC) is an annual review series commissioned by the International Society of Heterocyclic Chemistry (ISHC). Volumes in the series contain both highlights of the previous year's literature on heterocyclic chemistry and articles on emerging topics of particular interest to heterocyclic chemists. The chapters in Volume 21 constitute a systematic survey of the important original material reported in the literature of heterocyclic chemistry in 2008. Additional articles in this volume review "Biocatalytic approaches to chiral heterocycles" and "Ring-expanded ('fat') purines and their nucleoside/nucleotide analogues as broad-spectrum therapeutics." As with previous volumes in the series, Volume 21 apprises academic/industrial chemists and advanced students of developments in heterocyclic chemistry in a convenient format. * Covers the heterocyclic literature published in 2008 * Includes specialized reviews * Features contributions from leading researchers in their fields
When used in the context of reproduction of living cells the phrase "cell growth" is shorthand for the idea of "growth in cell populations by means of cell reproduction." During cell reproduction one cell (the "mother" cell) divides to produce two daughter cells. Cell proliferation, which depends on the intimately linked processes of growth and division, is a fundamental systems-level attribute of all life forms. The precise regulation of proliferation in response to internal and external cues is critical for development, tissue renewal and evolutionary fitness, while the disregulation of cell proliferation underlies a variety of human diseases, most notably cancer and ageing. Historically, ...