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Structure–Activity Relationships for Development of Neurokinin-3 Receptor Antagonists
This book explores the possible development of neurokinin-3 receptor (NK3R) antagonists with reduced environmental impact. Pharmaceuticals are used to cure diseases and to alleviate symptoms in humans and animals. However, the stable, bioactive substances excreted by patients have unfavorable effects on non-target species. To overcome these disadvantages of these highly stable, potent substances, drug design to turn off bioactivity after release into the environment is needed. The book describes the development of eco-friendly NK3R antagonists by introducing a labile functional moiety and substituting a scaffold. This resulted in a novel NK3R antagonist that oxidized into its inactive form w...
Neuroplasticity, Development, and Steroid Hormone Action
A compilation of cutting-edge research, Neuroplasticity, Development, and Steroid Hormone Action explores the effects of steroid hormones on brain development, function, and aging. The experimental approaches used by the authors ranges from molecular to behavioral and endocrine to neurobiological. It contains scientific photographs, line drawings, tables, color illustrations, and graphs, this interesting and timely text covers the neuroplastic effects of steroid hormones throughout the lifetime of various animal models, such as bees, fish, lizards, turtles, birds, mice, rats, and primates.
The International Corporate 1000
The International Corporate 1000 represents a joint venture between Monitor Publishing Com pany of Washington, DC, and Graham & Trotman Limited of London. Monitor Publishing Company is well known as the publisher of The Federal Yellow Book, The Congressional Yellow Book, and The Corporate 1000. Graham & Trotman's annual directories providing data on the major companies in many parts of the world are equally established. The two publishing companies have pooled their expertise in this joint venture to research, compile and publish The International Corporate 1000, A Directory o/Who Runs The World's 1000 Leading Corporations. The directory was designed to help you identify and contact the seni...
The John Coltrane Reference
The BBC's Jazz Book of the Year for 2008. Few jazz musicians have had the lasting influence or attracted as much scholarly study as John Coltrane. Yet, despite dozens of books, hundreds of articles, and his own recorded legacy, the "facts" about Coltrane's life and work have never been definitely established. Well-known Coltrane biographer and jazz educator Lewis Porter has assembled an international team of scholars to write The John Coltrane Reference, an indispensable guide to the life and music of John Coltrane. The John Coltrane Reference features a a day-by-day chronology, which extends from 1926-1967, detailing Coltrane's early years and every live performance given by Coltrane as either a sideman or leader, and a discography offering full session information from the first year of recordings, 1946, to the last, 1967. The appendices list every film and television appearance, as well as every recorded interview. Richly illustrated with over 250 album covers and photos from the collection of Yasuhiro Fujioka, The John Coltrane Reference will find a place in every major library supporting a jazz studies program, as well as John Coltrane enthusiasts.
Regulatory Issues Since 1964
First Published in 1994. Routledge is an imprint of Taylor & Francis, an informa company.
Report on the Operations of the Department of State (under Public Law 584)
Relates to the international educational exchange program and includes the executive agreements establishing the United States Educational Foundations and Commissions.
