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Prognostic and Predictive Factors in Autoimmune Connective Tissue Disorders
Autoimmune connective tissue diseases, including systemic lupus erythematosus, Sjögren’s syndrome, systemic sclerosis, dermatomyositis, rheumatoid arthritis, and mixed connective tissue diseases are complex conditions that commonly involve multiple organs and systems. The pathogenesis of many autoimmune diseases is elusive, and the disease course is extremely variable, with indolent or rapidly progressive case subsets. The heterogeneity and patient-to-patient variability of autoimmune connective tissue disease extend to their clinical manifestations, autoantibody profiles, speed of disease progression, the constellation of target organ effects, response to treatment, and survival. Despite...
New Insights into Autoinflammatory Diseases: From Bench to Bedside
Systemic autoinflammatory diseases (SAIDs) are a growing group of rare disorders caused by dysregulation of the innate immune system leading to episodes of organ-specific and systemic inflammation. Autoinflammation as a distinct disease category was first reported in 1999 as a group of monogenic disorders with resultant activation of the inflammasome and cytokine excess, presenting as periodic fever and inflammation in serous membranes. Since this original description, the focus has shifted considerably to the inclusion of complex multifactorial conditions, and more than 30 associated genes have been identified. Disease severity varies from mild to life threatening. Advances in the understanding of the pathogenetic role of interleukin-1, have opened new promising horizons in the treatment of these patients, and significantly altered disease outcome.
Il docile idioma
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Computational Science and Its Applications -- ICCSA 2013
The five-volume set LNCS 7971-7975 constitutes the refereed proceedings of the 13th International Conference on Computational Science and Its Applications, ICCSA 2013, held in Ho Chi Minh City, Vietnam in June 2013. The 248 revised papers presented in five tracks and 33 special sessions and workshops were carefully reviewed and selected. The 46 papers included in the five general tracks are organized in the following topical sections: computational methods, algorithms and scientific applications; high-performance computing and networks; geometric modeling, graphics and visualization; advanced and emerging applications; and information systems and technologies. The 202 papers presented in special sessions and workshops cover a wide range of topics in computational sciences ranging from computational science technologies to specific areas of computational sciences such as computer graphics and virtual reality.
Minimally Invasive Therapies for Endocrine Neck Diseases
This handy book offers a complete overview of current minimally invasive techniques for the management of endocrine diseases of the neck, reflecting how, in the past few years, the development of various ultrasound-guided procedures and endoscopic/video-assisted surgical techniques has changed the approach to thyroid and parathyroid diseases. The book opens by describing the main diagnostic tools for thyroid, parathyroid and cervical lymph nodes, focusing especially on the new technologies for tissue characterization. The different minimally invasive treatment procedures involving either a percutaneous approach (ethanol injection, laser thermal ablation, radiofrequency thermal ablation, high...
Advances in Agricultural and Industrial Microbiology
Diversity of microbial communities in soil and their multifaceted functionalities has paved the way for utilization of microbes in industries. This book comprises of soil microbial diversity and role of microbes in agro-industry. This volume is the compilation of the updated research from resource persons on impact of soil microbial diversity like increasing soil fertility, CO2 sequestration, and understanding soil microbial communities through cutting edge technology. Besides, the book embodies microbes renewed role in production of bioplastics, nutraceuticals, dairy products, drugs from macro-fungi, potential economic development from agrowaste or fish waste, and advance approaches in biop...
