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Immune privilege was once thought to be the property of a few select sites that include the eye, brain, testis, pregnant uterus and (of all things) the hamster cheek pouch, and was believed to be mainly based on sequestration behind blood-tissue barriers. This view has changed. Immune privilege is now considered to constitute a more general phenomenon through which tissues are able to actively direct and control immune responses taking place in their “territory” to preserve their structural and functional integrity in the face of inflammatory processes. These positive aspects of immune privilege can be hijacked by tumors to their survival advantage and to the detriment of the host. This Research Topic dissects the beneficial and deleterious consequences of immune privilege in terms of the cellular and molecular mechanisms that various tissues and tumors use, each in its own fashion, to regulate immune processes that affect them, at the local and the systemic level.
This book constitutes the refereed proceedings of the Second International Conference on Artificial Immune Systems, ICARIS 2003, held in Edinburgh, UK in September 2003. The 27 revised full papers presented were carefully reviewed and selected from 41 submissions. The book presents the first coherent account of the state of the art in artificial immune systems reserch. The papers are organized in topical sections on applications of artificial immune systems, immunocomputing, emerging metaphors, augmentation of artificial immune systems algorithms, theory of artificial immune systems, and representations and operators.
This is a pioneering work on the emerging field of artificial immune systems-highly distributed systems based on the principles of the natural system. Like artificial neural networks, artificial immune systems can learn new information and recall previously learned information. This book provides an overview of artificial immune systems, explaining its applications in areas such as immunological memory, anomaly detection algorithms, and modeling the effects of prior infection on vaccine efficacy.
Beginning his work on the monograph to be published in English, this author tried to present more or less general notions of the possibilities of mathematics in the new and rapidly developing science of infectious immunology, describing the processes of an organism's defence against antigen invasions. The results presented in this monograph are based on the construc tion and application of closed models of immune response to infections which makes it possible to approach problems of optimizing the treat ment of chronic and hypertoxic forms of diseases. The author, being a mathematician, had creative long-Iasting con tacts with immunologists, geneticist, biologists, and clinicians. As far back as 1976 it resulted in the organization of a special seminar in the Computing Center of Siberian Branch of the USSR Academy of Sci ences on mathematical models in immunology. The seminar attracted the attention of a wide circle of leading specialists in various fields of science. All these made it possible to approach, from a more or less united stand point, the construction of models of immune response, the mathematical description of the models, and interpretation of results.
This book constitutes the refereed proceedings of the 6th International Conference on Artificial Immune Systems, ICARIS 2007, held in Santos, Brazil, August 2007. The papers are organized in topical sections on search and optimization, classification and clustering, anomaly detection and negative selection, robotics, control and electronics. Modeling papers, conceptual papers, and technical papers and general applications are also included.
In the last few years the study of germinal centers of the lymphoid tissue has progressed at an accelerated pace. Questions about their role and their significance in immune responses that could not be answered, mainly because of tedmicallimitations, are presently approached experimentally from many different directions. Hypotheses, some more than half a century old, receive renewed attention. At this time, members of the Biology Division, Oak Ridge National Laboratory, U.S.A., and of the Institute of Pathology, University of Bern, Switzerland, decided to bring together workers interested in the field. The Conference was held in Bern, June 22-24, 1966, and included fifty-seven contributions ...
Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. - Provides solid scientific basis to our understanding of the associations between the brain and the immune system the importance of these connections - Presents coherent development from cellular and molecular neuroimmune communication to social and health considerations, including psychological intervention - Addresses the theory that there is a neurobiology of the immune system
The world keeps changing. There are always risks associated with change. To make careful risk assessment it is always needed to re-evaluate the information according to new findings in research. Scientific knowledge is essential in determining the strategy for fish farming. This information should be updated and brought into line with the required conditions of the farm. Therefore, books are one of the indispensable tools for following the results in research and sources to draw information from. The chapters in this book include photos and figures based on scientific literature. Each section is labeled with references for readers to understand, figures, tables and text. Another advantage of the book is the "systematic writing" style of each chapter. There are several existing scientific volumes that focus specially on fish farms. The book consists of twelve distinct chapters. A wide variety of scientists, researchers and other will benefit from this book.
This book constitutes the refereed proceedings of the 5th International Conference on Artificial Immune Systems, ICARIS 2006. The book presents 34 revised full papers, are organized in topical sections on computer simulation of classical immunology, computer simulation of idiotypic network, immunoinformatics conceptual papers, pattern recognition type of application, optimization type of application, control and time-series type of application, danger theory inspired application, and text mining application.