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The original, 11,000 kilometer journey from "From Sialkot to Vancouver", culminated on September 6, 1966. This book traces the history of Chaudhry Shakrullah Khan Bhindar and Sardar Begum Chandar of Sialkot, Pakistan whose descendants are now settled in Vancouver, Canada for over half a century.
Hereditary tyrosinemia type 1 (HT1), the most severe inborn error of the tyrosine degradation pathway, is due to a deficiency in fumarylacetoacetate hydrolase (FAH). The worldwide frequency of HT1 is one per 100,000 births, but some regions have a significantly higher incidence (1:1,800). The FAH defect results in the accumulation of toxic metabolites, mainly in the liver. If left untreated, HT1 is usually fatal before the age of two. HT1 patients develop several chronic complications including cirrhosis with a high risk of hepatocellular carcinoma (HCC) and neuropsychological impairment. Treatment comprises an inhibitor of the pathway, Nitisinone, a strict dietary treatment or liver transplantation. Early treatment is important to avoid HCC. The book includes the latest developments on the molecular basis of HT1, its pathology, screening and diagnosis and management of the disease written by leading scientists, geneticists, hepatologists and clinicians in the field.
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APPLIED WATER SCIENCE VOLUME 2 The second volume in a new two-volume set on applied water science, this book provides understanding, occurrence, identification, toxic effects and control of water pollutants in an aquatic environment using green chemistry protocols. The high rate of industrialization around the world has led to an increase in the rate of anthropogenic activities which involve the release of different types of contaminants into the aquatic environment. This generates high environmental risks, which could affect health and socio-economic activities if not treated properly. There is no doubt that the rapid progress in improving water quality and management has been motivated by ...
In 2019, the BJP came into power once again on the back of one of the most significant electoral mandates in recent years. Since then, the Narendra Modi-led government has seen a tumultuous few years as they have implemented far-reaching legislative changes including the Jammu and Kashmir Reorganisation Act, triple talaq, the Citizenship (Amendment) Act as well as farming laws. These laws, when implemented, caused widespread protests and upheaval across the country. While the country grappled with internal strife, it also faced challenges from its neighbours in the form of one of the most intense military stand-offs in decades after an unprovoked attack by China's People's Liberation Army at...