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The Pulmonary Neuroepithelial Body Microenvironment
This monograph sheds new light on pulmonary sensory receptors. Diving into the pulmonary microenvironment, the book focuses on the role of pulmonary neuroepithelial bodies (NEBs) as potential receptors and effectors, able to store and release neurotransmitters. It explores NEBs as potential stem cell niche and highlights the multidisciplinary approach taken to identify and study NEBs, including functional morphological investigation, live cell imaging, genetic models, and laser microdissection combined with gene expression analysis. Complexly organized NEBs are an integral part of the intrapulmonary airway epithelium of all air-breathing vertebrates. For decades a quest has been going on to ...
Novel Insights in the Neurochemistry and Function of Pulmonary Sensory Receptors
With the advances of immunohistochemistry in combination with confocal microscopy, airway sensory receptor end-organs can now be examined and evaluated objectively. Based on their ‘neurochemical coding’, morphology, location and origin, three sensory receptor end organs are currently morphologically well-characterised: smooth muscle-associated airway receptors (SMARs), neuroepithelial bodies (NEBs) and visceral pleura receptors (VPRs). The present information on the functional morphological and neurochemical characteristics of these sensory receptors, leads to important conclusions about their (possible) function.
Airway Chemoreceptors in Vertebrates
This book provides a comprehensive and up-to-date account of the information available on the morphological, physiological and evolutionary aspects of specialized cells distributed within the epithelia of the airways in the vertebrates. A lot of work has been done on the cell and molecular biology of these cells which are regarded as as oxygen receptor neuroepithelial cells. These chemoreceptors which were conserved throughout evolution have neuroendocrine functions carrying their signals to the central nervous system. The chemoreceptor cells are sensors which detect the signal changes in the external and internal environments, and play a key role in the survival of various species. Studies ...
Arterial Chemoreception
Arterial chemoreceptors are unique structures which continuously monitor changes in arterial blood oxygen, carbon dioxide, glucose, and acid. Alterations in these gases are almost instantaneously sensed by arterial chemoreceptors and relayed into a physiological response which restores blood homeostasis. Arterial Chemoreception contains updated material regarding the physiology of the primary arterial chemoreceptor; the carotid body. Moreover, this book also explores tantalizing evidence regarding the contribution of the aortic bodies, chromaffin cells, lung neuroepithelial bodies, and brainstem areas involved in monitoring changes in blood gases. Furthermore this collection includes data showing the critical importance of these chemoreceptors in the pathophysiology of human disease and possible therapeutic treatments. This book is a required text for any researcher in the field of arterial chemoreception for years to come. It is also a critical text for physicians searching for bench-to-bedside treatments for heart failure, sleep apnea, and pulmonary hypertension.
Neurologic Manifestations—Advances in Research and Treatment: 2013 Edition
Neurologic Manifestations—Advances in Research and Treatment: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Pain. The editors have built Neurologic Manifestations—Advances in Research and Treatment: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Pain in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Neurologic Manifestations—Advances in Research and Treatment: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Drugs During Pregnancy and Lactation
The care of pregnant women presents one of the paradoxes of modern medicine. Women usually require little medical intervention during an (uneventful) pregnancy. Conversely, those at high risk of damage to their own health or that of their unborn require the help of appropriate medicinal technology, including drugs. Accordingly, there are two classes of pregnant women, the larger group requires support but not much intervention, while the other needs the full range of diagnostic and therapeutic measures applied in any other branch of medicine. This book presents the current state of knowledge about drugs in pregnancy. In each chapter information is presented separately for two different aspects of the problem seeking a drug appropriate for prescription during pregnancy, and assessing the risk of a drug when exposure has already taken place. Practising clinicians who prescribe medicinal products to women who are, or who may become, pregnant, will find this volume an invaluable reference.
Inequalities and the Paradigm of Excellence in Academia
This volume examines the criteria of excellence producing inequalities of gender in the daily working environment and evaluation of academics. Policymakers have increasingly placed emphasis on gender equality as part of a strategy for achieving research excellence, and efforts to reduce gender bias have become mainstream. This book suggests that this goal has remained elusive in practice due to continuing under-representation of women across many academic and scientific fields. Questioning the old structures of male dominance still prevalent in national research policy, the book explores the effects of institutional values and practices on the careers of academics, particularly the academic ...
Behind the Scenes of Science
This book opens the black box of professorial recruitments and selection practices in the Netherlands, and unmasks some persistent myths to explain away the under- representation of women in professorial positions. These myths are unmasked by revealing gender practices such as gatekeeping, male networks and the constructs of excellence. This book challenges the view of an academic world where the allocation of rewards and resources is governed by the normative principles of transparency and meritocracy, and highlights the distance between the ideal ethos of science and the actuality of social interaction in appointment processes.
Work, Family and Childcare
"Studies the joint decisions made by parents regarding the time they allocate to paid employment and childcare. Extensive cross-national data is analysed from three countries that represent the diversity of European households: Belgium, Denmark and Spain. The book compares and contrasts the results and draws out important implications for European social policy"--Book jacket.
Current Research in Sports Sciences
There are two main reasons for pursuing research in the Sports Sciences. Firstly, by studying responses to exercise, we learn about the normal function of the tissues and or gans whose function allows exercise to be performed. The genetic endowment of elite ath letes is a major factor in their success, and they represent one end of the continuum of human performance capability: the study of elite athletes also demonstrates the limits of human adaptation because nowhere else is the body subjected to such levels of intensive exercise on a regular basis. The second reason for studying Sports Science is the intrinsic interest and value of the subject itself. Elite performers set levels to which ...
