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Quantum Physics and Life
This book reveals glimpses of how the quantum physics of atoms and molecules influences, and even controls, the way our cells function and how we and our fellow animals interact with our environment. Simply put, how birds fly and why grass grows. Certainly, biochemistry and molecular biology are the foundations for the biology of living cells, but there is more—quantum coherence and entanglement influencing the functioning of proteins and enzymes, and strictly speaking, without the quantum phenomena we wouldn’t even be here. In the end, however, this book is based on the solid ground of science, presenting the many fascinating phenomena of how quantum physics makes life possible without any unwarranted mystification.
Rethinking Cancer
Leading scientists argue for a new paradigm for cancer research, proposing a complex systems view of cancer supported by empirical evidence. Current consensus in cancer research explains cancer as a disease caused by specific mutations in certain genes. After dramatic advances in genome sequencing, never before have we known so much about the individual cancer cell--and yet never before has it been so unclear what to do with this knowledge. In this volume, leading researchers argue for a new theory framework for understanding and treating cancer. The contributors propose a complex systems view of cancer, presenting conceptual building blocks for a new research paradigm supported by empirical...
Physics of Life
The purpose of the book is to give a survey of the physics that is relevant for biological applications, and also to discuss what kind of biology needs physics. The book gives a broad account of basic physics, relevant for the applications and various applications from properties of proteins to processes in the cell to wider themes such as the brain, the origin of life and evolution. It also considers general questions of common interest such as reductionism, determinism and randomness, where the physics view often is misunderstood. The subtle balance between order and disorder is a repeated theme appearing in many contexts. There are descriptive parts which shall be sufficient for the comprehension of general ideas, and more detailed, formalistic parts for those who want to go deeper, and see the ideas expressed in terms of mathematical formulas.- Describes how physics is needed for understanding basic principles of biology- Discusses the delicate balance between order and disorder in living systems - Explores how physics play a role high biological functions, such as learning and thinking
Nobel Prizes and Life Sciences
The Nobel Prizes m natural sciences have achieved the reputation of being the ultimate accolade for scientific achievements. This honk gives a unique insight into the selection of Nobel Prize recipients, in particular the life sciences. The evolving mechanisms of selection of prize recipients are illustrated by reference to archives, which have remained secret for 1) years. Many of the prizes subjected to particular evaluation concern awards given for discoveries in the field of infectious diseases and the interconnected field of genetics. The book illustrates the individuals and environments that are conducive to scientific creativity. Nowhere is this enigmatic activity'-- the mime mover in advancing the human condition highlighted as lucidly as by identification individuals worthy of Nobel Prizes. --Book Jacket.
Epstein-Barr Virus and Human Disease
Since its discovery as the cause of infectious mononucleosis in 1964, the Epstein-Barr virus (EBV) has been etiologically implicated in an increasing number of human diseases. Generally considered the first human oncogenic virus because of a number of studies linking it with Burkitt's lymphoma and nasopharyngeal carcinoma (NPC), as well as its documented oncogenicity in nonhuman primates, EBVhas served as a model for identifying subsequent candidate oncogenic viruses and the stimulus for Evans' revision of the Henle-Koch postulates to accommodate the problems in proving viral oncogenicity in humans. Research on the role of EBV in human cancer was particularly en hanced (a) by the pioneering ...
Chromatin and Chromosomal Protein Research IV
Chromatin and Chromosomal Protein Research IV
Chromatin and Chromosomal Protein Research II
Chromatin and Chromosomal Protein Research II
Advances in Cancer Research
Academic Press proudly presents this Cumulative Subject Index covering Volumes 50-72 of Advances in Cancer Research. In one comprehensive source, the interested reader can find references to specific articles on topics such as breast cancer, prostate cancer, Kaposi's sarcoma, Burkitt's lymphoma, leukemias, oncogenes, transcription factors, tumor genetics, p53, T-cell receptors, and drug resistance. This cumulative index will serve not only as a complete overview of the major topics published in Advances in Cancer Research, but also as an indicator of the progress made in cancer research over the last ten years.
Tropomyosin
A recent review of one of my grant applications commented on the ‘rediscovery of tropomyosin’. I was tempted to write back in my rebuttal to the reviewer that I didn’t realise it had been lost. Uncharacteristic maturity prevailed and I resisted the temptation, but I was struck by the underlying observation that research on the str- ture and function of tropomyosin has been somewhat invisible, particularly in terms of the cytoskeleton isoforms. So, how can it be that one of the two major components of the actin filament has been so thoroughly overlooked? I suspect that the answer is disappointingly pedestrian. Whereas the biochemistry of the 1980s revealed the potential of tropomyosin i...
