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The book depicts the various roles of platelets in a variety of cardio-metabolic diseases. Traditional and non-traditional platelet functions are described in detail in atherosclerosis, metabolic syndrome, diabetes, myocardial infarction, and other vascular pathologies. Particular focus is put on platelets as a link between haemostasis and inflammation contributing to both. Last but not least the books links the most recent advances in basic sciences with promising novel therapeutic applications and first results of clinical trials. The book is written for biomedical scientists in the sub disciplines vascular biology, biochemistry and immunology; and it as well will be of interest and value for academic physicians like cardiologists, hematologists, general internists and vascular surgeons.
This book is a comprehensive guide to the latest advances and techniques in vascular and endovascular surgery. Divided into nineteen chapters, the book begins with discussion on translational vascular research, new oral anticoagulants, and statins. The following sections provide detailed explanations of both common and more complex surgical procedures used in the treatment of vascular disorders and diseases. Highly illustrated with nearly 200 clinical images and tables, the book presents the experiences of vascular specialists worldwide. Key Points Comprehensive guide to the latest advances and techniques in vascular and endovascular surgery Covers both common and more complex surgical procedures Includes discussion on translational vascular research, new oral anticoagulants, and statins Highly illustrated with nearly 200 clinical images and tables
This book constitutes the refereed conference proceedings of the 21st International Conference on the Applications of Evolutionary Computation, EvoApplications 2018, held in Parma, Italy, in April 2018, collocated with the Evo* 2018 events EuroGP, EvoCOP, and EvoMUSART. The 59 revised full papers presented were carefully reviewed and selected from 84 submissions. EvoApplications 2018 combined research from 14 different domains: business analytics and finance (EvoBAFIN); computational biology (EvoBIO); communication networks and other parallel and distributed systems (EvoCOMNET); complex systems (EvoCOMPLEX); energy-related optimization (EvoENERGY); games and multi-agent systems (EvoGAMES); image analysis, signal processing and pattern recognition (EvoIASP); realworld industrial and commercial environments (EvoINDUSTRY); knowledge incorporation in evolutionary computation (EvoKNOW); continuous parameter optimization (EvoNUM); parallel architectures and distributed infrastructures (EvoPAR); evolutionary robotics (EvoROBOT); nature-inspired algorithms in software engineering and testing (EvoSET); and stochastic and dynamic environments (EvoSTOC).
Klaus-Dieter Petersen ist einer der erfolgreichsten Spieler der Handball-Bundesliga. In 340 Länderspielen für Deutschland schnürte er ein großes Erlebnispaket. Der gebürtige Niedersachse prägt eine große Ära beim Turnverein Hassee Winterbek, kurz THW genannt. Er ist Spieler, Co-Trainer und Jugendkoordinator in Kiel und zeigt den Zebras, wie man Titel gewinnt. Petersen schwingt sich bei den vielen Feiern oft zum Zeremonienmeister auf. Seine umgestalteten Lieder animieren nach den Erfolgen auf dem Rathausbalkon, Rathausplatz und in der Innenstadt zum Mitmachen. In detailreichen Episoden wird das Leben des Vollbluthandballers erzählt. »Pitti« öffnet in diesem Buch seine Schatzkammer der Erinnerungen und bittet den Leser zur Tür herein. Mit einem Vorwort von Uwe Schwenker.
This book explores when, why, and how regional organizations adopt and design institutions to promote and protect fundamental standards of democracy, human rights, and rule of law in their member states. These regional institutions have spread globally. While their institutional designs have become increasingly similar over time, regional particularities persist. The book identifies factors that generate the demand for regional institutions and shape its institutional design. The argument combines hitherto juxtaposed explanatory factors of demands and diffusion by integrating them in a single framework and clarifying under what conditions the interplay between demands and diffusion plays out in the adoption and design of regional institutions. The book provides a comprehensive overview of regional democracy, human rights, and rule of law institutions based on two original datasets and draws on multivariate statistical analysis as well as case studies on the making and change of regional institutions in the Organization of American States and the Organization of African Unity/African Union.