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First multi-year cumulation covers six years: 1965-70.
This book gives an update on the inhibitory mechanisms involved in the various steps of hematopoietic stem cell proliferation and differentiation. The authors report the latest research advances, factors that control the cell cycle, receptors function, molecular approaches, the in vivo and in vitro effects of several inhibitors, the inhibition of hematopoiesis by viruses, protecting the bone marrow. The book contains the latest results published by the best international specialists and will be fascinating reading for all those interested in this subject.
This book contains the 17 lectures given at the International Symposium on Liver Cells and Drugs held in Rennes on 7 to 10 July 1987 as well as 50 communications presented at the poster sessions.
Papers in English and French, some with summary in French.
Multimodal interface systems make it possible to interact with computers using speech and hearing, touch and gesture. The role of vision in human computer interaction could therefore be brought back to its natural place in communication. In many applications, non-visual presentation methods could be used efficiently to provide more natural human-computer interfaces. This evolution is of particular relevance for the visually handicapped. The purpose of this book is to provide a complete understanding of state-of-the-art research in non-visual human-computer interaction. The book is aimed at all researchers and developers interested in improving the accessibility of software applications, especially for people with disabilities.
This valuable reference work provides a synthesis of the latest knowledge about the acrosomatic reaction of human sperm. The acrosomatic reaction, which is a fundamental step in the process of fertilisation, is examined on both the fundamental and clinical levels. Three very recent aspects are also dealt with: what happens to the acrosome during intracytoplasmic microinjections, the usefulness of screening spermatozoa that have completed their acrosomatic reaction, and the development of contraception by a vaccine that targets one of the proteins of the acrosome. International Symposium, Collioure, France, September 1995.
Includes proceedings of the first European Symposium on platelet immunology held in Paris, Palais du Luxembourg (France), 1 to 2 March 1990."
Although everybody had and will experience anxiety, its intensity, frequency and characteristics may vary from what can be considered as "normal" to pathological. The development of benzodiazepine as anxiolytics has been a major step firstly in therapeutics and secondly in the understanding of the associated biological mechanisms. Recently, new drugs without secondary effects of benzodiazepines have been developed. The purpose of the book was to take stock of the present knowledge: clinical aspects of pathological anxiety, neurobiological mechanisms associated with stress and anxiety, molecular targets of potent anxiolytic drugs, new issues and directions.
Many questions were raised during this multidisciplinary meeting during which geneticists, haematologists, embryologists, immunologists, transplant surgeons and physicians exchanged views on these questions. The second part of the meeting was devoted to an examination of the mechanisms of medullary deficiency. A more clinical approach was taken to the epidemiological, molecular and genetic aspects of medullary deficiency. There was also discussion of various therapeutic methods, including transplants, the use of haematopoietic growth factors, immunosuppressive treatments and gene therapy. Proceedings of the joint international workshop on "Foetal and neonatal hematopoiesis and mechanisms of bone marrow failure", Paris, April 1995.