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Although everybody had and will experience anxiety, its intensity, frequency and characteristics may vary from what can be considered as "normal" to pathological. The development of benzodiazepine as anxiolytics has been a major step firstly in therapeutics and secondly in the understanding of the associated biological mechanisms. Recently, new drugs without secondary effects of benzodiazepines have been developed. The purpose of the book was to take stock of the present knowledge: clinical aspects of pathological anxiety, neurobiological mechanisms associated with stress and anxiety, molecular targets of potent anxiolytic drugs, new issues and directions.
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The Mesolimbic Dopamine System: From Motivation to Action Edited by P. Willner Psychology Department, City of London Polytechnic, London, UK and J. Scheel-Krüger Psychopharmacological Research Laboratory, St Hans Hospital, Roskilde, Denmark The mesolimbic dopamine system is a system of neurons innervating the ventral forebrain, which utilizes dopamine as its principal neurotransmitter. In recent years this system has become one of the most heavily researched pathways within the brain, particularly in relation to its potential involvement in major psychiatric disorders, such as schizophrenia, mania, depression and drug dependence. This volume provides a unique and timely multidisciplinary synthesis of our current knowledge of the anatomy, pharmacology, physiology and behavioural functions of the mesolimbic system, and its operation in health and mental disorder.
Bulletin des lois, 2e partie. Ordonnances, 1e et 2e section
La conscience du nouveau-né, Le critère électrophysiologique en médecine néo-natale dans les hôpitaux parisiens 1946-1976. Dialectique de la nature pensante : la construction de la cognition mathématique. L'anxiété, un pont entre l'épilepsie et la mémoire ? Au Sujet d'une modalité particulière de recours à l'activité physique les procédés autocalmants. Les Molécules phéromonales : Éléments d'épistémologie historique. Vers une stratégie de formalisation de la rupture dans l'interaction verbale. Sur la notion de programme génétique