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Heritable Human Genome Editing
  • Language: en
  • Pages: 239

Heritable Human Genome Editing

Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, ...

Human Germline Modification and the Right to Science
  • Language: en
  • Pages: 681

Human Germline Modification and the Right to Science

  • Categories: Law

A survey of the regulation of human germline genome modification in eighteen countries and the emerging international standards.

Human Genome Editing
  • Language: en
  • Pages: 329

Human Genome Editing

Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are in place to govern these technologies and how and when the public should be engaged in these decisions. Human Genome Editing considers important questions about the human a...

CRISPR People
  • Language: en
  • Pages: 395

CRISPR People

  • Type: Book
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  • Published: 2022-03-01
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  • Publisher: MIT Press

What does the birth of babies whose embryos had gone through genome editing mean--for science and for all of us? In November 2018, the world was shocked to learn that two babies had been born in China with DNA edited while they were embryos—as dramatic a development in genetics as the 1996 cloning of Dolly the sheep. In this book, Hank Greely, a leading authority on law and genetics, tells the fascinating story of this human experiment and its consequences. Greely explains what Chinese scientist He Jiankui did, how he did it, and how the public and other scientists learned about and reacted to this unprecedented genetic intervention. The two babies, nonidentical twin girls, were the first ...

Rewriting Nature
  • Language: en
  • Pages: 441

Rewriting Nature

  • Categories: Law

Rewriting Nature is a cogent, riveting interdisciplinary exploration of the law, science, and policy of emerging genome-editing technology.

Altered Inheritance
  • Language: en
  • Pages: 305

Altered Inheritance

With the advent of CRISPR gene-editing technology, designer babies have become a reality. Françoise Baylis insists that scientists alone cannot decide the terms of this new era in human evolution. Members of the public, with diverse interests and perspectives, must have a role in determining our future as a species.

Mitochondrial Replacement Techniques
  • Language: en
  • Pages: 201

Mitochondrial Replacement Techniques

Mitochondrial replacement techniques (MRTs) are designed to prevent the transmission of mitochondrial DNA (mtDNA) diseases from mother to child. While MRTs, if effective, could satisfy a desire of women seeking to have a genetically related child without the risk of passing on mtDNA disease, the technique raises significant ethical and social issues. It would create offspring who have genetic material from two women, something never sanctioned in humans, and would create mitochondrial changes that could be heritable (in female offspring), and therefore passed on in perpetuity. The manipulation would be performed on eggs or embryos, would affect every cell of the resulting individual, and onc...

The Better Half
  • Language: en
  • Pages: 288

The Better Half

  • Type: Book
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  • Published: 2020-04-07
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  • Publisher: Penguin UK

An award-winning physician and scientist makes the game-changing case that genetic females are stronger than males at every stage of life 'A powerful antidote to the myth of a "weaker sex"' Gina Rippon, author of The Gendered Brain From birth, genetic females are better at fighting viruses, infections and cancer. They do better at surviving epidemics and famines. They live longer, and even see the world in a wider variety of colours. These are the facts; they are simply stronger than men at every stage of life. Why? And why are we taught the opposite? Drawing on his wide-ranging experience and cutting-edge research as a medic, geneticist and specialist in rare diseases, Dr Sharon Moalem reveals how the answer lies in our genetics: the female's double XX chromosomes offer a powerful survival advantage. And he calls for a long-overdue reconsideration of our one-size-fits-all view of the body and medicine - a view that still frames women through the lens of men. Revolutionary, captivating and utterly persuasive, The Better Half will make you see women, men and the survival of our species anew. 'Brilliant, original and groundbreaking, highly readable and genuinely useful' Daily Mail

Patients with Passports
  • Language: en
  • Pages: 526

Patients with Passports

  • Categories: Law

The world may be getting smaller every day, but until very recently health care remained local. 'Patients with Passports' is the first comprehensive legal and ethical analysis of one part of the globalization of health care: medical tourism. The author examines the two sides of the industry: medical tourism for services legal in the patient's home country where patients travel to places such as India, Thailand and Mexico to reduce costs, avoid queues, or qualify for insurance incentives, and medical tourism for services illegal in the home country.

International Ethical Guidelines for Health-Related Research Involving Humans
  • Language: en

International Ethical Guidelines for Health-Related Research Involving Humans

"In the new 2016 version of the ethical guidelines, CIOMS provides answers to a number of pressing issues in research ethics. The Council does so by stressing the need for research having scientific and social value, by providing special guidelines for health-related research in low-resource settings, by detailing the provisions for involving vulnerable groups in research and for describing under what conditions biological samples and health-related data can be used for research."--Page 4 de la couverture.