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The first comprehensive reference to focus on the molecular development and treatment of the disease, Molecular Oncology of Breast Cancer provides authoritative information across the spectrum of modern breast cancer research and clinical care. Edited by two world-class experts in cancer pathology, drug development, and patient management, with contributions from over 50 experts, this ground-breaking text describes the genes, proteins, and biologic pathways that are being evaluated today and will be tested in the future to derive the molecular signature of each newly diagnosed breast cancer. For the first time, readers can now obtain, in a single volume, up-to-date information on how molecular-based tests are being used to identify predisposition, provide earliest detection, decide classification based on genetic fingerprint and predict therapy-specific outcomes. MOBC includes unique chapters on functional imaging and the impact of targeted therapies on the FDA approval process. This book gives readers vital, up-to-date information on important molecular discoveries that affect the everyday management of the breast cancer patient.
The fourth edition of Clinical Nuclear Medicine highlights the continued growth in clinical applications for PET and other aspects of molecular imaging. With its problem-oriented clinical approach, the book presents relevant topics of current importance to the practicing clinician rather than providing a comprehensive review of all technical a
In the 25-40% of the general female population with radiodense breast parenchyma, clinically occult lesions may be invisible in the screen-film mammogram. Even if suspicious masses are detected, determination of the benign or malignant nature of a mass is often impossible from the x-ray image. There is thus a need for diagnostic procedures that can noninvasively help characterize suspicious breast lesions. Scintimammography is an imaging technique that shows promise as an adjunct diagnostic tool in problem solving mammography, for monitoring recurrence after surgery, and in the assessment of multidrug-resistance. However, because clinical Anger cameras have only moderate spatial resolution a...
Demonstrating the role of nuclear medicine as a complementary technique to mammography and other imaging modalities for the diagnosis of breast cancer, Radionuclide Imaging of the Breast provides a comprehensive overview of scintimammography-an accurate, safe, and noninvasive imaging method for the evaluation of breast lesions and malignancies. Reveals the encouraging results of multicenter clinical trials in the U.S. and Canada using 99mTc sestamibi breast imaging for the diagnosis of primary breast carcinoma! Addressing nonsurgical sampling of nonpalpable breast lesions as an effective means of providing diagnostic and prognostic information, Radionuclide Imaging of the Breast discusses in...