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This is the first book addressing in full the most important aspects of the angiotensin-(1-7), the key peptide of the protective axis and the main component in the new modulatory concept of the renin-angiotensin system. It features a detailed review of angiotensin-(1-7) and its receptor Mas, comprising the historical background, enzymatic pathways for generation, functions, integrative aspects of its protective profile, and its therapeutic potential. It also encompasses a comprehensive presentation of current knowledge about its widespread biological actions on several tissues, as well as the most recent scientific achievements, emerging from preclinical and clinical trials. Dr. Santos is a ...
This book constitutes the refereed proceedings of the Third Latin American Workshop, LAWCN 2021, held in Sao Luis do Maranhao, Brazil, during December 8–10, 2021. The 13 full papers and 3 short papers included in this book were carefully reviewed and selected from 27 submissions. They were organized in topical sections as follows: Interdisciplinary applications of Artificial Intelligence (AI) and Machine Learning (ML); AI and ML applied to robotics; AI and ML applied to biomedical sciences; Health issues and computational neuroscience; Software and hardware implementations in neuroscience; and Neuroengineering – science and technology.
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This work is a guidebook for clinicians who are involved in treating depressive patients and also serves the research scientists who are working on the psychopharmacological mechanisms of antidepressant actions and psychopathological mechanisms underlying mood disorders. Mood disorders such as major depressive disorder (MDD), bipolar disorder (BPD) and seasonal affective disorder (SAD) are the most disabling disorders that are among the most expensive of all medical illnesses. The pathophysiology of mood disorders is very complex and involves many mechanisms like circadian rhythm disruption, sleep abnormalities, melatonin rhythm abnormalities and alterations in melatonin receptor mechanisms,...
Focusing on three key stages of the criminal justice process, discipline, punishment and desistance, and incorporating case studies from Asia, the Americas, Europe, Africa and Australia, the thirteen chapters in this collection are based on exciting new research that explores the evolution and adaptation of criminal justice and penal systems, largely from the early nineteenth century to the present. They range across the disciplinary boundaries of History, Criminology, Law and Penology. Journeying into and unlocking different national and international penal archives, and drawing on diverse analytical approaches, the chapters forge new connections between historical and contemporary issues i...
Latin America plays an increasingly important role in the development of modern Christianity yet it has been underrepresented in current scholarship on religion and science. In this first book on the subject, contributors explore the different ways that religion and science relate to each other.
A geographical encyclopedia of world place names contains alphabetized entries with detailed statistics on location, name pronunciation, topography, history, and economic and cultural points of interest.
This publication is a two-yearly report on trends in the steelmaking capacity of economies that are not members of the OECD. This report examines existing steelmaking capacity and investments that will lead to changes in capacity by 2014.