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This book provides a thorough and up-to-date overview of the aryl hydrocarbon receptor (AHR) and its unique dual role in toxicology and biology. The coverage includes epigenetic mechanisms, gene expression, reproductive and developmental toxicity, signal transduction, and transgenic animal models. Featuring an internationally recognized team of authors at the forefront of AHR research, this resource provides a comprehensive reference for readers interested in understanding the full spectrum of AHR, from basic concepts, toxicology analysis, and models to polymorphism and related diseases.
A pro-p group is the inverse limit of some system of finite p-groups, that is, of groups of prime-power order where the prime - conventionally denoted p - is fixed. Thus from one point of view, to study a pro-p group is the same as studying an infinite family of finite groups; but a pro-p group is also a compact topological group, and the compactness works its usual magic to bring 'infinite' problems down to manageable proportions. The p-adic integers appeared about a century ago, but the systematic study of pro-p groups in general is a fairly recent development. Although much has been dis covered, many avenues remain to be explored; the purpose of this book is to present a coherent account of the considerable achievements of the last several years, and to point the way forward. Thus our aim is both to stimulate research and to provide the comprehensive background on which that research must be based. The chapters cover a wide range. In order to ensure the most authoritative account, we have arranged for each chapter to be written by a leading contributor (or contributors) to the topic in question. Pro-p groups appear in several different, though sometimes overlapping, contexts.
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
This second edition preserves the introductory spirit of the first edition while roughly doubling the amount of material covered. The topics of the first edition have been enhanced with additional discussion, new numerical experiments, and improved figures. New topics in the second edition include nonlinear equations, Neumann boundary conditions, variable mesh and variable coefficient problems, anisotropic problems, algebraic multigrid (AMG), adaptive methods, and finite elements. This introductory book is ideally suited as a companion textbook for graduate numerical analysis courses. It is written for computational mathematicians, engineers, and other scientists interested in learning about multigrid.
For the past 25 years the CADE conference has been the major forum for the presentation of new results in automated deduction. This volume contains the papers and system descriptions selected for the 17th International Conference on Automated Deduction, CADE-17, held June 17-20, 2000,at Carnegie Mellon University, Pittsburgh, Pennsylvania (USA). Fifty-three research papers and twenty system descriptions were submitted by researchers from ?fteen countries. Each submission was reviewed by at least three reviewers. Twenty-four research papers and ?fteen system descriptions were accepted. The accepted papers cover a variety of topics related to t- orem proving and its applications such as proof ...