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Enhancement of Industrial Energy Efficiency and Sustainability
Industrial energy efficiency has been recognized as a major contributor, in the broader set of industrial resources, to improved sustainability and circular economy. Nevertheless, the uptake of energy efficiency measures and practices is still quite low, due to the existence of several barriers. Research has broadly discussed them, together with their drivers. More recently, many researchers have highlighted the existence of several benefits, beyond mere energy savings, stemming from the adoption of such measures, for several stakeholders involved in the value chain of energy efficiency solutions. Nevertheless, a deep understanding of the relationships between the use of the energy resource and other resources in industry, together with the most important factors for the uptake of such measures—also in light of the implications on the industrial operations—is still lacking. However, such understanding could further stimulate the adoption of solutions for improved industrial energy efficiency and sustainability.
Molecular Pathology of Early Cancer
This book describes the principles and the application of the existing molecular methodology for the detection of early cancer. Discussion focuses on the molecular changes characterizing preneoplastic lesions; molecular targets for early detection; validation of molecular targets; and new diagnostic technology for early detection. The advantages of molecular detection over current methods are examined, as well as the importance of identifying and characterizing preneoplastic lesions. In addition to the uses of highly specific molecular probes to detect early cancer, this book demonstrates the many ways in which molecular markers serve oncology. While meeting pressing needs in the practice of medicine, molecular detection of early cancer scientifically necessitates a confrontation with the biology of cancer, such as the genetic determinants of progression, regression, dormancy, and invasion. This work not only discusses the diagnostic value of these molecular methods but views their practical benefits against a background of conventional morphology.
Neuroscience: From the Molecular to the Cognitive
This hundredth volume is a commemorative milestone in the prestigeous Progress in Brain Research series. Accordingly, authors were invited to write on any topic, given that their choice represented the topic most near and dear to their own efforts over a significant period of the recent past, and to which they would likely continue to be devoted in the future.In that sense, this volume does not represent a scientific meeting, but rather an overview sample of problems and methodologies that epitomize brain research broadly at this special moment in the maturation of the field.The chapters comprising this volume assort themselves readily into five or six established categories of topics: developmental brain research, molecular brain research, integrative brain research, neuroplasticity, and neuro-psychiatric conditions.This volume reports through a sample of recognized leaders in the neuroscientific community at a significant instant in the history and evolution of the field.
Advances in Immunology
Advances in Immunology, a long established and highly respected serial, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.
Neurodegenerative Disorders as Systemic Diseases
This book sheds new light on neurodegenerative disorders as systemic diseases. Classically, neuronal cell death was a hallmark of such disorders. However, it has become evident that neural dysfunction is more important in the pathophysiology of neurodegenerative disorders. More recently, the prionoid-spreading hypothesis of disease-causing molecules has attracted a great deal of attention. Therapeutic strategies thus must be reconsidered in the light that neurodegenerative disorders are indeed systemic diseases. The first part of this book introduces the concept of neurodegeneration in biology and pathophysiology. The second part focuses on clinical evaluation and biomarkers from the perspective of this new concept, while the third summarizes the risk factors of neurodegeneration. The fourth part of this work indicates future directions of treatment, and the final part discusses health promotion for prevention and quality of life. This book will be of interest to both researchers and medical personnel, and provides a fresh approach to neurodegenerative diseases, paving the way to new research and improved quality of health care for patients.
Diabetes Digital Health, Telehealth, and Artificial Intelligence
Diabetes Digital Health, Telehealth, and Artificial Intelligence explains how to develop and use the emerging technologies of digital health, telehealth, and artificial intelligence to address this important public health problem to deliver new hardware, software, and processes. The book explores trends in developing and deploying the three most important emerging technologies for diabetes: digital health, telehealth, and artificial intelligence. This book is essential to clinicians, scientists, engineers, industry professionals, regulators, and investors, offering the tools that will be used to create the next generation products to support a precision medicine approach to manage diabetes. ...
Fundamentals of Bile Duct Injuries
Bile duct injuries (BDI) are considered the most serious surgical complication associated with cholecystectomy. According to different reports, its incidence has remained constant over the years, ranging from 0.1% to 0.9%. BDI is associated with a greater risk of perioperative morbidity and mortality, a reduction in the quality of life, and a decrease in long-term survival. Also, this complication is a concern to surgeons since its progression is uncertain and may lead to demands on professional responsibility ("malpractice") and emotional and physical consequences ("second victim"). Given that injuries in a high percentage of patients are initially unsuspected, the postoperative recovery ma...
Clinical Textbook of Mood Disorders
A comprehensive overview of the research status, diagnosis, and management of mood disorders, including depression and bipolar disorder.
Minding Glial Cells in the Novel Understandings of Mental Illness
Traditionally, abnormalities of neurons and neuronal networks including synaptic abnormalities and disturbance of neurotransmitters have dominantly been believed to be the main causes of psychiatric disorders. Recent cellular neuroscience has revealed various unknown roles of glial cells such as astrocytes, oligodendrocytes and microglia. These glial cells have proved to continuously contact with neurons /synapses, and have been shown to play important roles in brain development, homeostasis and various brain functions. Beyond the classic neuronal doctrine, accumulating evidence has suggested that abnormalities and disturbances of neuron-glia crosstalk may induce psychiatric disorders, while...
Frontiers in Clinical Drug Research - Alzheimer Disorders
Frontiers in Clinical Drug Research - Alzheimer Disorders is an e-Book series concerned with Alzheimer's disease (AD) that causes dementia, or loss of brain function. The disease affects the parts of the brain that deal with memory, thought, and language. Chapters in each volume focus on (Alzheimer Disorders) drug research with special emphasis on clinical trials, research on drugs in advanced stages of development and cure for Alzheimer’s disease and related disorders. Frontiers in Clinical Drug Research - Alzheimer Disorders will be of particular interest to readers interested in drug therapy of this specific neurodegenerative condition and related brain disorders as the series provides relevant reviews written by experts in field of Alzheimer’s Disease research. The fourth volume of this series features research on - Melatoninergic Pathways in Alzheimer's disease, - Nutritional Approaches in Alzheimer’s disease prevention, - Updates on drugs and strategies for Alzheimer’s disease prevention
