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Molecular Genetics and Emerging Therapies for Epithelial Ovarian Cancer: Basic Research and Clinical Perspectives
  • Language: en
  • Pages: 348

Molecular Genetics and Emerging Therapies for Epithelial Ovarian Cancer: Basic Research and Clinical Perspectives

Epithelial ovarian cancer (EOC) is the most lethal gynecological disorder due to a lack of effective early detection strategies. Worldwide, approximately 230,000 women are diagnosed annually, whereas 150,000 die. It represents the seventh most commonly diagnosed cancer among women in the world with 5-year survival rate of 46%. More than one-fifth of EOC have been related to hereditary conditions. Considerable efforts have been made to implement screening of the general population to diagnose EOC early; nevertheless, this has been ineffective and there is no approved strategy. Nowadays, new approaches for early diagnosis and prevention based on molecular genomics are in development. Whole gen...

Oncogenomics and Cancer Proteomics
  • Language: en
  • Pages: 242

Oncogenomics and Cancer Proteomics

Oncogenomics and Cancer Proteomics - Novel Approaches in Biomarkers Discovery and Therapeutic Targets in Cancer presents comprehensive reviews of the most common cancers from bench to bedside applications by an international team of experts. This book will contribute to the scientific and medical community by providing up-to-date discoveries of oncogenomics and their potential applications in cancer translational research. It is intended for students, scientists, clinicians, oncologists and health professionals working in cancer research.

Non-coding RNAs in Breast Cancer
  • Language: en
  • Pages: 158

Non-coding RNAs in Breast Cancer

None

Breast Cancer Metastasis and Drug Resistance
  • Language: en
  • Pages: 415

Breast Cancer Metastasis and Drug Resistance

​This volume comprehensively covers recent prrogress in breast cancer research. In an effort to successfully treat breast cancer, it is imperative to a) fully understand the disease with all its heterogeneity, b) understand the factors that influence the metastasis of breast cancer to distant organs making it lethal and c) understand the underlying processes that lead to the phenomenon of drug-resistance making the disease particularly incurable. The book explores all of these issues, including the phenomenon of epithelial-mesenchymal-transition, cancer stem cells as well as microRNAs in an attempt to better understand the disease in connection to its heterogeneity/metastasis/drug-resistance as well as to propose novel signaling pathways for therapeutic intervention. The profiling of tumors to molecularly classify breast cancers is also investigated so that customized targeted therapies can be developed. ​

Nanomedicines for Breast Cancer Theranostics
  • Language: en
  • Pages: 440

Nanomedicines for Breast Cancer Theranostics

  • Type: Book
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  • Published: 2020-03-08
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  • Publisher: Elsevier

Nanomedicines for Breast Cancer Theranostics addresses the translational aspects and clinical perspectives of breast cancer nanomedicine from a multidisciplinary perspective. The book summarizes research efforts at the preclinical and clinical stage of nanostructures and nanomedicine for dealing with the important challenge of nanomedicine translation in breast cancer theranostics. This book is an important resource for those working in both academia and industry, focusing on hot topics in biomaterials, biomedical engineering, drug delivery and oncology. - Shows how the discovery of new nanomedicines is leading directly to an increase in the early-stage diagnosis of breast cancer - Includes coverage of breast cancer nanomedicine standardization and characterization, highlighting newly developed treatments, diagnostics and treatment monitoring tools - Explains why the design of nanobiomaterials make them effective drug carriers when treating breast cancer

Protein Kinase Inhibitors
  • Language: en
  • Pages: 832

Protein Kinase Inhibitors

Protein Kinase Inhibitors: From Discovery to Therapeutics offers a foundational, pragmatic overview of protein kinases inhibitors and their potential role in disease modulation and treatment. Here, international experts in the field offer an integrated discussion of kinase inhibitor biology, biomarker discovery, and methods for drug design and development. After a brief overview of kinases and kinase inhibitors, subsequent chapters discuss individual kinases that are representative of the wider kinases and kinase families, including their roles in disease pathogenesis, underlying mechanisms, potential inhibitors and their modes of action for therapeutic modulation. Several potential drugs un...

The Molecular Basis of Cancer E-Book
  • Language: en
  • Pages: 1040

The Molecular Basis of Cancer E-Book

2015 BMA Medical Book Awards Highly Commended in Oncology Category!The Molecular Basis of Cancer arms you with the latest knowledge and cutting-edge advances in the battle against cancer. This thoroughly revised, comprehensive oncology reference explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of this disease. A team of leading experts thoroughly explains the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Detailed descriptions of topics from molecular abnormalities in common cancers to new approaches for cancer therapy equip...

Annual Meeting Proceedings
  • Language: en
  • Pages: 954

Annual Meeting Proceedings

  • Type: Book
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  • Published: 2006
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  • Publisher: Unknown

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Cumulated Index Medicus
  • Language: en
  • Pages: 1484

Cumulated Index Medicus

  • Type: Book
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  • Published: 1992
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  • Publisher: Unknown

None

Leishmaniasis
  • Language: en
  • Pages: 422

Leishmaniasis

  • Type: Book
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  • Published: 2016-10-14
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  • Publisher: CRC Press

This new volume provides exhaustive knowledge on a wide range of natural products and holistic concepts that have provided promising in the treatment of leishmaniasis. Including the major natural therapies as well as traditional formulations, over 300 medicinal plants and 150 isolated compounds that are reported to have beneficial results in the treatment of the disease are explored in this comprehensive work. This book also acts as an important resource on various anti-inflammatory plants used to treat various inflammatory conditions of the disease.