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This volume is based on a meeting of the Fondation IPSEN, held in Paris on Sep tember 18, 1995 to address the main issues of nervous system stem cells biology. Cell replacement in the adult mammals is not unusual outside the nervous sys tem. In fact, the nervous system is unique in lacking the ability to replace cells, following damage. Most neurons, in the adult central nervous system are termin of the organism and are not replaced ally differentiated, exist through the life when they die. There are, however, regions of the postnatal brain that continue to produce new neurons, but the fate and longevity of those cells are not well known. Evidence exists that small populations of neurons con...
Cell and Gene Therapies for Neurologic Diseases, Volume 205 comprehensively covers the scientific background, translational efforts, clinical developments and registered biologics that have entered into clinical practice. Coverage includes types of therapies available and in development, and best practice uses for a variety of neurological disorders including Parkinson's, Huntington's, ALS, stroke, spinal cord RP, demyelination, and epilepsy. As the emergence of gene and cellular therapeutics has changed the clinical landscape for a variety of disorders, and is now ready to do so for neurological diseases, these therapeutic modalities currently complement, and may in time, supplant small molecule drugs. - Summarizes advances in cell and gene therapy for neurological diseases - Describes the therapies available and in development - Includes surgical, ethical, and manufacturing considerations - Identifies best practices for specific neurological diseases - Covers Huntington's, Parkinson's, ALS, Stroke, Demyelination, epilepsy, and more
Praise for the Series:"Full of interest not only for the molecular biologist - for whom the numerous references will be invaluable - but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell."--British Medical Journal - Provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology - Contributions from leaders in their fields - Abundant references
This volume provides a comprehensive, state-of-the art review of the field of cell therapy. The volume begins with an overview of the breadth of the field and then turns to overviews of imaging technologies that can aid in both safety and efficacy evaluations. The book then turns to numerous contributions detailing the rapidly growing field of stem cell therapies. These sections cover our understanding of the natural roles of stem cells in biology and human disease and then touches on several of the more prominent areas where stem cells are moving rapidly into clinical evaluation including neurodegenerative diseases, muscular dystrophy, cardiac repair, and diabetes. The volume concludes with...
Evaluation of Analytical Methods in Biological Systems
Bringing together the leading future figures in ethics broadly construed with essays ranging from metaethics and normative ethics to applied ethics and political philosophy, topics include new work on experimental philosophy, feminism, and global justice incorporating perspectives informed from historical and contemporary approaches alike.
This book constitutes the thoroughly refereed post-conference proceedings of the 6th IFIP WG 13.6 Working Conference on Human Work Interaction Design, HWID 2021, held in Beijing, China, in May, 2021. The 10 revised and extended full papers presented were carefully selected for inclusion in this volume. The papers deal with the analysis and interaction design of a variety of complex work and life contexts found in different business and application domains. They focus on interaction design for work engagement taking usability of interactive systems to the next level by providing employees pleasurable and meaningful experiences via the tools used at work. The papers are organized the following topical sub-headings: Trends in human Work Interaction Design; Workplace & work experience Analysis for Interaction Design; and Artificial Intelligence (AI) for Human Work.
International Symposium Held at the Department of Anatomy and Cytology Justus Liebig Universität in Gießen, July 30 - August 1, 1986