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Index Medicus
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Hospital-Based Health Technology Assessment
A timely work describing how localized hospital-based health technology assessment (HB-HTA) complements general, ‘arms-length’ HTA agency efforts, and what has been the collective global impact of HB-HTA across the globe. While HB-HTA has gained significant momentum over the past few years, expertise in the field, and information on the operation and organization of HB-HTA, has been scattered. This book serves to bring this information together to inform those who are currently working in the field of HTA at the hospital, regional, national or global level. In addition, this book is intended for decision-makers and policy-makers with a stake in determining the uptake and decommissioning ...
Advances in Computational Toxicology
This book provides a comprehensive review of both traditional and cutting-edge methodologies that are currently used in computational toxicology and specifically features its application in regulatory decision making. The authors from various government agencies such as FDA, NCATS and NIEHS industry, and academic institutes share their real-world experience and discuss most current practices in computational toxicology and potential applications in regulatory science. Among the topics covered are molecular modeling and molecular dynamics simulations, machine learning methods for toxicity analysis, network-based approaches for the assessment of drug toxicity and toxicogenomic analyses. Offering a valuable reference guide to computational toxicology and potential applications in regulatory science, this book will appeal to chemists, toxicologists, drug discovery and development researchers as well as to regulatory scientists, government reviewers and graduate students interested in this field.
Essential Manual of 24-Hour Blood Pressure Management
ESSENTIAL MANUAL OF 24-HOUR BLOOD PRESSURE MANAGEMENT Hypertension is one of the greatest threats to human health. The World Health Organization (WHO) estimates that 1.13 billion people worldwide have hypertension. In 2017, new guidelines for managing hypertension were published by the American Hypertension Association (AHA), guidelines which lowered the diagnosis thresholds of hypertension, and thereby increased the prevalence of hypertension. As such, hypertension is now recognized as a more serious and widespread a condition than ever before. In this new edition of the Essential Manual of 24-Hour Blood Pressure Management, the author emphasizes that lowering the blood pressure (BP) and re...
Recent Developments in Lie Algebras, Groups and Representation Theory
This book contains the proceedings of the 2009-2011 Southeastern Lie Theory Workshop Series, held October 9-11, 2009 at North Carolina State University, May 22-24, 2010, at the University of Georgia, and June 1-4, 2011 at the University of Virginia. Some of the articles, written by experts in the field, survey recent developments while others include new results in Lie algebras, quantum groups, finite groups, and algebraic groups.
Knowledge-based Software Engineering
Addresses various topics in the context of knowledge-based software engineering, including challenges that have arisen in this area of research. This book includes topics such as knowledge-based requirements engineering, domain analysis and modeling; development processes for knowledge-based applications; and, knowledge acquisition.
Neural Functions of the Delta-Opioid Receptor
This book is the first to summarize the progress of research on neural functions of the the delta opioid receptor (DOR) to date. This receptor, a member of the opioid receptor family, was traditionally thought to be primarily involved in pain modulation. Recent new findings have shown its unique role in neuroprotection and many other functions. Many scientists from a number of independent laboratories have now confirmed that DOR can provide neuroprotection against hypoxic/ischemic injuries. They have also found that it plays a role in a variety of physiological and pathophysiological events such as hypoxic encephalopathy, epilepsy, acupuncture, Parkinson's disease, etc. by regulating ionic homeostasis, glutamate transportation and signaling, and balancing intracellular survival/death signals. The book will provide a comprehensive overview of the current state of DOR research and provide a blueprint for future directions.
