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This volume is the product of a February 1982 conference, cosponsored by the American Heart Association, the National Institutes of Health, and the Bowman Gray School of Medicine, which examined techniques for delineating quantitatively the natural history of atherosclerosis. Against the background of current pathologic and clinical knowledge of atherosclerosis, invasive and noninvasive evaluative methods now in use and under development are surveyed in depth. Correlative clinicopathologic studies of atherosclerosis pose special questions with respect to both luminal and plaque characteristics that are addressed in this volume. An old observa tion, based on the examination of arterial casts,...
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From a historical point of view the first studies on the response of the organism to stressful situations in general, and on the psychobiology of stress in particular, are probably those of Cannon and de la Paz, the physiologists who showed in 1911 that the adrenal medulla and the sympathetic system are involved in emergency situations. Cannon noted that the venous blood of cats frightened by barking dogs contained adrenaline, a response of the organism which was prevented by adrenalectomy or by section of the splanchnic nerve innervating the adrenal medulla. Cannon suggested that the adrenal medulla was acting in concert with the sympathetic nervous system, so that both systems were activat...
This volume contains nearly all the papers presented at the AMS-IMS-SIAM Joint Summer Research Conference on Biofluiddynamics, held in July 1991, at the University of Washington, Seattle. The lead paper, by Sir James Lighthill, presents a comprehensive review of external flows in biology. The other papers on external and internal flows illuminate developments in the protean field of biofluiddynamics from diverse viewpoints, reflecting the field's multidisciplinary nature. For this reason, the work should be useful to mathematicians, biologists, engineers, physiologists, cardiologists and oceanographers alike. The papers highlight a number of problems that have remained largely unexplored due to the difficulty of addressing biological flow motions, which are often governed by large systems of nonlinear differential equations and involve complex geometries. However, recent advances in computational fluid dynamics have expanded opportunities to solve such problems. These developments have increased interest in areas such as the mechanisms of blood and air flow in humans, the dynamic ecology of the oceans, animal swimming and flight, to name a few.
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