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Redox Proteomics
Methodology and applications of redox proteomics The relatively new and rapidly changing field of redox proteomics has the potential to revolutionize how we diagnose disease, assess risks, determine prognoses, and target therapeutic strategies for people with inflammatory and aging-associated diseases. This collection brings together, in one comprehensive volume, a broad array of information and insights into normal and altered physiology, molecular mechanisms of disease states, and new applications of the rapidly evolving techniques of proteomics. Written by some of the finest investigators in this area, Redox Proteomics: From Protein Modifications to Cellular Dysfunction and Diseases exami...
Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors
In 1971, Vane proposed that the mechanism of action of the aspirin-like drugs was through their inhibition of prostaglandin biosynthesis. Since then, there has been intense interest in the interaction between this diverse group of inhibitors and the enzyme known as cyclooxygenase (COX). It exists in two isoforms, COX-l and COX-2 (discovered some 5 years ago). Over the last two decades several new drugs have reached the market based on COX-l enzyme screens. Elucidation of the three-dimensional structure of COX-l has provided a new understanding for the actions of COX inhibitors. The constitutive isoform of COX, COX-l has clear physiological functions. Its activation leads, for instance, to th...
Family Forest: Public Version Volume 3 E-G
The result of more than twenty years' research, this seven-volume book lists over 23,000 people and 8,500 marriages, all related to each other by birth or marriage and grouped into families with the surnames Brandt, Cencia, Cressman, Dybdall, Froelich, Henry, Knutson, Kohn, Krenz, Marsh, Meilgaard, Newell, Panetti, Raub, Richardson, Serra, Tempera, Walters, Whirry, and Young. Other frequently-occurring surnames include: Greene, Bartlett, Eastman, Smith, Wright, Davis, Denison, Arnold, Brown, Johnson, Spencer, Crossmann, Colby, Knighten, Wilbur, Marsh, Parker, Olmstead, Bowman, Hawley, Curtis, Adams, Hollingsworth, Rowley, Millis, and Howell. A few records extend back as far as the tenth century in Europe. The earliest recorded arrival in the New World was in 1626 with many more arrivals in the 1630s and 1640s. Until recent decades, the family has lived entirely north of the Mason-Dixon Line.
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Index Medicus
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
