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J. Mendel, 1822-1884
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Gregor Mendel
Gregor Mendel, the founder of genetics, is renowned as one of the world’s most ingenious and influential scientists. Nonetheless, he remains misunderstood and enigmatic, his history shrouded in controversy and myth. Escaping poverty, he joined a scholarly community of Augustinian friars in a monastery and studied at the University of Vienna under some of Europe’s most accomplished scientists. He returned to a tumultuous milieu at the monastery as he and his fellow friars suffered a harrowing investigation accusing them of secularism and pantheistic philosophy. Against this backdrop, Mendel initiated an epic set of experiments with the common garden pea that would lead him to reveal the m...
Ending the Mendel-Fisher Controversy
In 1865, Gregor Mendel presented "Experiments in Plant-Hybridization," the results of his eight-year study of the principles of inheritance through experimentation with pea plants. Overlooked in its day, Mendel's work would later become the foundation of modern genetics. Did his pioneering research follow the rigors of real scientific inquiry, or was Mendel's data too good to be true—the product of doctored statistics? In Ending the Mendel-Fisher Controversy, leading experts present their conclusions on the legendary controversy surrounding the challenge to Mendel's findings by British statistician and biologist R. A. Fisher. In his 1936 paper "Has Mendel's Work Been Rediscovered?" Fisher ...
SETs
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Standing on the Shoulders of Darwin and Mendel
Standing on the Shoulders of Darwin and Mendel: Early Views of Inheritance explores early theories about the mechanisms of inheritance. Beginning with Charles Darwin's now rejected Gemmule hypothesis, the book documents the reception of Gregor Mendel's work on peas and follows the work of early 20th century scholars. The research of Francis Galton, a cousin of Darwin, and the friction it caused between these two are a part of longer story of the development of genetics and an understanding of how offspring inherit the characteristics of their parents. Bateson, Garrod, de Vries, Tschermak and others are all characters in a scientific story of discovery, acrimony, cooperation and revelation.
Darwin and Mendel
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The Red Book
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Metalloenzymes
Metalloenzymes: From Bench to Bedside offers a thorough overview of metalloenzymes, spanning biochemical and structural features, pharmacology, and biotechnological applications. After a brief overview, international experts in the field discuss a wide range of magnesium, calcium, zinc, manganese, nickel, iron, copper, cadmium, molybdenum, and tungsten enzymes, along with catalytic roles within their active sites. With a uniform approach throughout, each chapter includes the structure and function of the enzyme, physiologic and pathologic roles, inhibitors and activators of the enzyme (and their design), and clinical agents or compounds applied in medicine and drug discovery. This book enables scientists across academia and industry to adopt ongoing metalloenzyme research, and continuous discovery of novel metalloenzymes, in new life science studies and clinical applications. - Examines a range of metalloenzymes, from biochemistry to pharmacology and drug design - Each chapter examines enzyme structure and function, physiologic and pathologic roles, inhibitors and activators, and clinical application - Features chapter contributions from international experts in the field
The London Gazette
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