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As a capstone of the commemorations of the 40th anniversary of the birth of the first baby conceived by in vitro fertilization (IVF), in 1978, this collection gathers the principal actors of the history of IVF, and summarizes the main achievements, current state, and future prospects of this technique. The contributions here cover, in a historical perspective, all major aspects of IVF, including its indications and techniques, the basic concepts of ovarian stimulation, the cryopreservation of embryos and oocytes, oocyte in vitro maturation, and technical aspects of oocyte retrieval and embryo transfer, among many other topics. The volume not only provides topical information to health professionals, but is written in such a way that it is understandable to the lay public who may read it as a passionate story of the evolution of techniques intimately related to the origin of human life.
The advent of assisted conception procedures such as in-vitro fertili sation (IVF) has provided the impetus for exploration of the factors that lead to the establishment of pregnancy. This collection of papers from leading research workers brings together current concepts of the processes which may be of importance in implantation. The complex signals from the embryo to the ovary, endometrium and myometrium are now being revealed through studies in both primates and other mammalian species. This book addresses the interrelationship of pituitary and ovarian hormones in controlling ovulation and the preparation of the intrauterine environment for implantation. Once fertilisation has occurred a...
A variety of new techniques that promise to revolutionize the clinical management of early pregnancy are fully detailed in this state-of-the-art book. Leading international researchers describe fast-moving topics such as embryo manipulation and the diagnosis of congenital abnormalities. The technology of assisted reproduction has made it possible to study living embryonic material for the first time, which has led to rapid advances in our understanding of the human embryo's early development. For example, study of the embryo in the test tube has pointed to early pregnancy loss as a possible cause of later infertility. Even more important, diagnostic tests using sophisticated techniques of mo...
Male infertility is a clinician-orientied book aimed at the clinician dealing with the infertile couple because rational, effective management is only possible if the couple are considered together. The aim of the work is to provide advice to the clinician and to give reference to the underlying science. This will not only enable clinicians to understand the underlying science but will also give scientists an insight to clinical work. This blend of science and clinical work is reflected in the contributors who are experts drawn from both fields.
The examination of the human fallopian tubes was, until recently, restricted to observations on gross anatomical disposition and tubal patency. These studies, for decades, were the domain of doctors and physiologists whose primary interest was population control and family planning, funded largely by organisations and agencies seek ing alternatives to steroidal contraceptives. For a "worrying" but short period after the birth of Louise Brown in 1978 as the conse quence of successful in-vitro fertilisation and embryo transfer, the fallopian tube was considered to be "dispensable" given that the metabolic milieu in which human fertilisation takes place could be effortlessly reproduced in a Pet...
This is an enlarged, updated, color-illustrated new edition of the definitive clinical reference on in vitro fertilization and assisted reproduction. It contains 37 chapters by top-ranked specialists from around the world covering every aspect of investigation and therapeutic options as taught and practiced at the world-famous Bourn Hall Clinic. Large format, double-column pages. Includes bibliographic references, procedures, protocols and information sheets, and index.
This volume of essays, together with its companion Conceiving the Embryo: Ethics, Law and Practice in Human Embryology (Martinus Nijhoff, The Hague, 1996, ISBN 90-411-0208-6) is the result of a concerted action in the BIOMED programme of the European Commission, which was coordinated by the Editor. Clinicians, lawyers and philosophers explore the theoretical and practical problems presented by the new technologies in assisted human reproduction in Eastern, Central and Western Europe. The essays reveal considerable dissonance in existing and proposed legislation, both within and between European countries, and examine the rights of parents and children involved in these new procedures.
In spite of the fact that the process of meiosis is fundamental to inheritance, surprisingly little is understood about how it actually occurs. There has recently been a flurry of research activity in this area and this volume summarizes the advances coming from this work. All authors are recognized and respected research scientists at the forefront of research in meiosis. Of particular interest is the emphasis in this volume on meiosis in the context of gametogenesis in higher eukaryotic organisms, backed up by chapters on meiotic mechanisms in other model organisms. The focus is on modern molecular and cytological techniques and how these have elucidated fundamental mechanisms of meiosis. ...
Intrauterine insemination (IUI), also known as artificial insemination, is a fertility treatment that uses a catheter to place washed sperm directly into the uterus. Its aim is to increase the number of sperm reaching the fallopian tubes and subsequently increase the chances of fertilisation (American Pregnancy Association). The second edition of Intrauterine Insemination brings physicians and trainees fully up to date with the latest developments in the technique. Divided into 48 chapters, this comprehensive guide covers every aspect of the procedure, from patient selection and clinical assessment of couples, to ovarian induction, predictors of ovarian response, modulation of sperm motility, and sperm banking. The final sections describe data management issues, sex pre-selection, and regulation of assisted reproductive technologies. Key points New edition presenting latest developments in IUI Covers all aspects of the procedure Includes more than 150 images, illustrations and tables Previous edition published in 2005