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This incisive Handbook provides a global update on the state of knowledge in cooperatives and mutuals, expertly describing future directions for research and education. Showcasing extensive discussions of cooperative theory, Matthew S. Elliott and Michael A. Boland, and the contributors, assess cooperatives' social, economic and environmental effects and analyse the impact of regional and cultural features that make cooperatives unique.
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Provides insight into the involvement of free radicals in the pathogenesis of chemical-induced toxic tissue injury. The text addresses the fundamentals of free radical chemistry and the theoretical basis for electron transfer reaction leading to free radical generation. It describes the various subcellular sources of free radicals, the biological reactivity with lipid, protein and nucleic acids, and the physiochemical determinants of free radical-induced cell injury and the various antioxidant defence systems. The book focuses on target organ toxicity, and the concluding section offers an overview of the evidence implicating free radicals in the aetiology of various chemical toxicities, challenging the possibility of misguided use of biomarkers for oxidative damage.