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Knobil and Neill's Physiology of Reproduction
The Fourth Edition of Knobil & Neill continues to serve as a reference aid for research, to provide the historical context to current research, and most importantly as an aid for graduate teaching on a broad range of topics in human and comparative reproduction. In the decade since the publication of the last edition, the study of reproductive physiology has undergone monumental changes. Chief among these advances are in the areas of stem cell development, signaling pathways, the role of inflammation in the regulatory processes in the various tissues, and the integration of new animal models which have led to a greater understanding of human disease. The new edition synthesizes all of this n...
Transgenic Models in Endocrinology
The dramatic recent expansion in genomic information has motivated the development of new approaches to characterize gene expression and function. A critical issue for both basic and clinical endocrinologists is the physiological role of genes involved in regulating endocrine functions. Transgenic technologies allow the translation of genotypic information into specific phenotypes by using gene overexpression or loss of specific gene functions. Murine functional genomics is thus of central importance in modem biomedical endocrine research. Although mice are at present, the preferred mammalian species for genetic manipulations because of the availability of pluripotent embryonic. stem cells a...
Kisspeptin Signaling in Reproductive Biology
Kisspeptin has been shown to be both necessary and sufficient for activation of the reproductive axis, during puberty and later in adulthood. This makes kisspeptin a fundamental component of the reproductive axis. Kisspeptin has been deemed the single most potent stimulator of GnRH neurons yet known. The importance of kisspeptin has been documented in humans as well as non-human animal models, ranging from monkeys, sheep, and rodents to numerous fish species, thus signifying a highly conserved nature of its reproductive function. Importantly, kisspeptin neurons seem to mediate many of the regulatory effects of other signals, whether they are metabolic, circadian, hormonal, or stress. This places kisspeptin neurons in a unique position to be key nodal points and conduits for conveying numerous endogenous and exogenous signals to the reproductive axis.
Global Mental Health
This is the definitive textbook on global mental health, an emerging priority discipline within global health, which places priority on improving mental health and achieving equity in mental health for all people worldwide.
Handbook of Psychology, Developmental Psychology
Psychology is of interest to academics from many fields, as well as to the thousands of academic and clinical psychologists and general public who can't help but be interested in learning more about why humans think and behave as they do. This award-winning twelve-volume reference covers every aspect of the ever-fascinating discipline of psychology and represents the most current knowledge in the field. This ten-year revision now covers discoveries based in neuroscience, clinical psychology's new interest in evidence-based practice and mindfulness, and new findings in social, developmental, and forensic psychology.
Essentials of Functional MRI
During the last two decades, new developments in functional MRI (magnetic resonance imaging) have made it possible to detect changes in the brain over time, as opposed to the "snapshot" produced by conventional MRI. Essentials of Functional MRI breaks down the technical challenges for physicians, researchers, and technologists who use functional MR
Imaging in Neurodegenerative Disorders
This text summarizes the latest developments in imaging techniques and other new diagnostic methods as applied to the neurodegenerative disorders.
ABC of the First Year
This well-established book gives clear guidance on normal development and how to diagnose and manage illness in newborn infants and babies. The sixth edition of the ABC of the First Year has been fully revised and updated to reflect the introduction of National Institute for Health and Clinical Excellence guidelines, the reduction in universal screening and the increasing care of the newborn provided by family practitioners and midwives. There are new sections on the recognition and prevention of obesity, which is an increasing problem. The reduction in universal screening has resulted in parents requesting advice about their child's development at a variety of ages. A Development Chart show...
