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The Cervical Spine is the most comprehensive, current, and authoritative reference on the cervical spine. Prepared by internationally recognized members of The Cervical Spine Research Society Editorial Committee, the Fifth Edition presents new information, new technologies, and advances in clinical decision making. The text provides state-of-the-art coverage of basic and clinical research, diagnostic methods, and medical and surgical treatments, bringing together the latest thinking of the foremost orthopaedic surgeons, neurosurgeons, neurologists, rheumatologists, radiologists, anatomists, and bioengineers. Chapters cover anatomy, physiology, biomechanics, neurologic and functional evaluation, and radiographic evaluation and address the full range of pediatric problems, fractures, spinal cord injuries, tumors, infections, inflammatory conditions, degenerative disorders, and complications. Accompanying the text is a website with the fully searchable text plus a color image bank.
The Retinoids, Volume 1 covers the chemistry and biology of retinoids, with an emphasis on the role of retinoids in nutrition and in vision. After briefly discussing the discovery and nomenclature of retinoids, this six-chapter volume describes the chemical and physical properties of natural and synthetic retinoids, as well as the retinoidal benzoic acid derivatives. The book goes on describing various reactions with radioisotopes for the synthesis of retinoids and related compounds. Considerable chapters explain the chemical, physical, and biological methodologies for separating and measuring retinoids. A discussion on the relationships between structure and activity of retinoids is included. The last chapter addresses the role of vitamin A in animal and human nutrition. This volume also discusses the metabolism of vitamin A in normal and disease states, as well as its interaction with hormones, micronutrients, drugs, and alcohol. This volume is an ideal source for nutritionists, clinicians, and researchers who are interested in the progressing field of retinoid research.
Features: The book covers the heavy metal impact on plants in detail. Chapters cover an array of topics and issues related to heavy metal pollution and its management strategies by plants Recent research results and some pointers to future advancements in current topic.
Epigenetic changes are heritable and reversible modifications that significantly affect gene expression without any change in DNA sequence. The epigenetic signature is remodelled during the lifespan as a direct consequence of both environment and lifestyle. Therefore, health or disease status strongly depends on epigenetic marks. This book summarizes the current knowledge in the field and includes chapters on epigenetics in plants and epigenetics in health and disease. It is written for a wide audience of basic and clinical scientists, teachers and students interested in gaining a better understanding of epigenetics.
BENEFICIAL CHEMICAL ELEMENTS OF PLANTS Understand beneficial elements and their role in the future of botany and agriculture Beneficial elements are those which, while not essential to plant life, can provide stimulation and enhance plant growth. Properly harnessed, these elements can bolster plant growth in the face of environmental conditions—including drought, nutrient deficiency, and excessive soil salinity—and biotic stresses like pathogens and animal activity. As climate change and population growth pose increasingly serious challenges to agriculture and essential plant production, it has never been more important to unleash the potential of beneficial elements. Beneficial Chemical...
This book is a printed edition of the Special Issue "Feature Papers" that was published in Processes
Handbook of Pharmacogenomics and Stratified Medicine is a comprehensive resource to understand this rapidly advancing field aiming to deliver the right drug at the right dose to the right patient at the right time. It is designed to provide a detailed, but accessible review of the entire field from basic principles to applications in various diseases. The chapters are written by international experts to allow readers from a wide variety of backgrounds, clinical and non-clinical (basic geneticists, pharmacologists, clinicians, trialists, industry personnel, ethicists) to understand the principles underpinning the progress in this area, the successes, failures and the challenges ahead. To be a...
This book presents, in 26 chapters, the status quo in epigenomic profiling. It discusses how functional information can be indirectly inferred and describes the new approaches that promise functional answers, collectively referred to as epigenome editing. It highlights the latest important advances in our understanding of the functions of plant epigenomics and new technologies for the study of epigenomic marks and mechanisms in plants. Topics include the deposition or removal of chromatin modifications and histone variants, the role of epigenetics in development and response to environmental signals, natural variation and ecology, as well as applications for epigenetics in crop improvement. Discussing areas ranging from the complex regulation of stress and heterosis to the precise mechanisms of DNA and histone modifications, it presents breakthroughs in our understanding of complex phenotypic phenomena.
Abiotic stresses such as drought (water deficit), extreme temperatures (cold, frost and heat), salinity (sodicity) and mineral (metal and metalloid) toxicity limit productivity of crop plants worldwide and are big threats to global food security. With worsening climate change scenarios, these stresses will further increase in intensity and frequency. Improving tolerance to abiotic stresses, therefore, has become a major objective in crop breeding programs. A lot of research has been conducted on the regulatory mechanisms, signaling pathways governing these abiotic stresses, and cross talk among them in various model and non-model species. Also, various ‘omics’ platforms have been utilize...