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The riddle of the biochemical nature of drug dependence of the opiate type has stimulated many studies directed toward understanding the molecular basis of the action of opiates, and, particularly, the phenomena of tolerance, physical dependence, and drug-seeking behavior-phenomena exhibited by man and experimental animals exposed persistently to these drugs. The results of these studies provided a substantial body of information which has been published in the scientific and medical literature. The purely pharma cological responses in man and animals to the opiates have been described and evaluated in many monographs and text-books of pharmacology. However, there is no single source for spe...
This book provides an exciting history of the discovery of Ramsey Theory, and contains new research along with rare photographs of the mathematicians who developed this theory, including Paul Erdös, B.L. van der Waerden, and Henry Baudet.
This book constitutes the thoroughly refereed post-proceedings of the Japanese Conference on Discrete Computational Geometry, JCDCG 2001, held in Tokyo, Japan in November 2001. The 35 revised papers presented were carefully reviewed and selected. Among the topics covered are polygons and polyhedrons, divissible dissections, convex polygon packings, symmetric subsets, convex decompositions, graph drawing, graph computations, point sets, approximation, Delauny diagrams, triangulations, chromatic numbers, complexity, layer routing, efficient algorithms, and illumination problems.
Computer graphics has been advancing to the level of creating completely new worlds inside computers. Through such computer graphics worlds, we human beings now have far improved insight into wide varieties of real worlds starting from fairly simple but exact worlds of curves and surfaces and reaching to complex human worlds. This volume presents a quite concrete and advanced methods, techniques, modeling and mathematical backgrounds which are indispensable in order to carry out end researches to increase insight through computer graphics.
The use of natural catalysts - enzymes - for the transformation of non-natural is not at all new: they have been used for more man-made organic compounds than one hundred years, employed either as whole cells, cell organelles or isolated enzymes [1]. Certainly, the object of most of the early research was totally different from that of the present day. Thus the elucidation of biochemical pathways and enzyme mechanisms was in the foreground of the reasearch some decades ago. It was mainly during the 1980s that the enormous potential of applying natural catalysts to transform non-natural organic compounds was recognized. What started as a trend in the late 1970s could almost be called a fashio...
This revised and enlarged fifth edition features four new chapters, which contain highly original and delightful proofs for classics such as the spectral theorem from linear algebra, some more recent jewels like the non-existence of the Borromean rings and other surprises. From the Reviews "... Inside PFTB (Proofs from The Book) is indeed a glimpse of mathematical heaven, where clever insights and beautiful ideas combine in astonishing and glorious ways. There is vast wealth within its pages, one gem after another. ... Aigner and Ziegler... write: "... all we offer is the examples that we have selected, hoping that our readers will share our enthusiasm about brilliant ideas, clever insights ...
This book is the result of a 25-year-old project and comprises a collection of more than 500 attractive open problems in the field. The largely self-contained chapters provide a broad overview of discrete geometry, along with historical details and the most important partial results related to these problems. This book is intended as a source book for both professional mathematicians and graduate students who love beautiful mathematical questions, are willing to spend sleepless nights thinking about them, and who would like to get involved in mathematical research.
The fields of integer programming and combinatorial optimization continue to be areas of great vitality, with an ever increasing number of publications and journals appearing. A classified bibliography thus continues to be necessary and useful today, even more so than it did when the project, of which this is the fifth volume, was started in 1970 in the Institut fur Okonometrie und Operations Research of the University of Bonn. The pioneering first volume was compiled by Claus Kastning during the years 1970 - 1975 and appeared in 1976 as Volume 128 of the series Lecture Notes in Economics and Mathematical Systems published by the Springer Verlag. Work on the project was continued by Dirk Hau...
This book was written with the purpose of providing a sound basis for the design of enzymatic reactions based on kinetic principles, but also to give an updated vision of the potentials and limitations of biocatalysis, especially with respect to recent app- cations in processes of organic synthesis. The ?rst ?ve chapters are structured in the form of a textbook, going from the basic principles of enzyme structure and fu- tion to reactor design for homogeneous systems with soluble enzymes and hete- geneous systems with immobilized enzymes. The last chapter of the book is divided into six sections that represent illustrative case studies of biocatalytic processes of industrial relevance or pot...