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Colwell, the first female director of the National Science Foundation, discusses the entrenched sexism in science, the elaborate detours women have taken to bypass the problem, and how to fix the system. When she first applied for a graduate fellowship in bacteriology, she was told, "We don't waste fellowships on women." Over her six decades in science, as she encounters other women pushing back against the status quo, Colwell also witnessed the advances that could be made when men and women worked together. Here she offers an astute diagnosis of how to fix the problem of sexism in science-- and a celebration of the women pushing back. --
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New Bacterial Vaccines focuses upon unfulfilled needs for bacterial vaccines. The increase in drug resistance among many bacterial species has increased the need for new bacterial vaccines. This book serves as a comprehensive reference on the major aspects of developing new bacterial vaccines. The distinctive feature of this book is that it focuses upon new vaccines now under development by reviewing key issues for each vaccine target and new technologies being applied to developing new vaccines. This book should prove useful for students in the life sciences, scientists, developers of vaccines and biotechnology products, clinicians, regulators, and health-care practitioners.
This volume describes the structure and function of bacterial toxins and presents a comprehensive review of virulence factors, providing recent information concerning cell physiology and biochemistry, as well as new toxin tools for experimental studies and clinical therapy. A wide variety of toxic proteins, including the toxins that cause diptheria, cholera, pertussis, shigellosis, tetanus, botulism and anthrax, are discussed.;The work is aimed at microbiologists, biochemists, endocrinologists, toxicologists, infectious disease specialists, pathologists, public health officials, and upper-level undergraduate and graduate students in these disciplines.
The process of developing nucleic acid probes for infectious agents and novel methods of detecting the binding of probes to the target DNA and RNA are reviewed in this thorough volume. Probes to a wide variety of bacterial, viral and protozoan pathogens are presented in detail by the leaders of this dynamic field. Also presented is the use of probes for antimicrobial susceptibility testing of bacteria and other infectious agents. The impact of the high cost of this technology on the clinical microbiology laboratory and on the food industry, versus the potential benefits of early diagnosis or recognition of contaminated foodstuffs, is considered. This volume is indispensable to those who work in the field of infectious diseases, including pathologists, microbiologists and infectious disease clinicians. In addition, food microbiologists will also find this volume to be a useful resource.
This book covers the role of peptide mediators in the intestinal responses to infectious and inflammatory challenges presented by diverse disease states, including inflammatory bowel disease and infectious diarrheas and dysenteries, and the epidemiology and pathogenesis of cholera and related diarrheal diseases. The more than 40 papers included in the volume are written by leading researchers working on cytokines and mucosal responses. The papers are the results of interactive scientific research between investigators from the U.S. and Japan, through a group of panels focusing on the following specific areas of interest: Malnutrition, which recognizes the role of nutrition in human health an...