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Bronchiectasis is a hot topic in respiratory medicine, attracting an increasing amount of interest from clinicians, scientists, physiotherapists and the pharmaceutical industry. However, there is a lack of knowledge about the disease in terms of the research performed, clinical management, classification and patient treatment. The disease is also very complex because it can be caused by multiple underlying disorders, meaning its clinical presentation is highly diverse. This Monograph will tackle these issues by providing a series of chapters from recognised world experts covering: clinical management, service delivery, pathophysiology, microbiology and underlying disorders. The book also addresses the challenges faced in clinical trials and the need for drug development, and presents a number of clinical cases designed to aid learning. The Bronchiectasis Monograph substantially integrates the 2017 ERS guidelines on management of these patients. It is an essential reference for anyone caring for bronchiectasis patients or engaged in bronchiectasis research.
This work provides a thought-provoking account of how medical treatments can be tested with unbiased or 'fair' trials and explains how patients can work with doctors to achieve this vital goal. It spans the gamut of therapy from mastectomy to thalidomide and explores a vast range of case studies.
Official records produced by the armies of the United States and the Confederacy, and the executive branches of their respective governments, concerning the military operations of the Civil War, and prisoners of war or prisoners of state. Also annual reports of military departments, calls for troops, correspondence between national and state governments, correspondence between Union and Confederate officials. The final volume includes a synopsis, general index, special index for various military divisions, and background information on how these documents were collected and published. Accompanied by an atlas.
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The field of acute exacerbations in chronic respiratory disease is challenging: definitions of acute exacerbations differ amongst the diseases and their severity has proven difficult to define. The Guest Editors of this Monograph tackle this challenging area by bringing together articles from internationally recognised experts in the field of acute exacerbations in chronic lung diseases. The book is separated into three sections: the first considers the definition, severity and consequences of exacerbations in each disease; the second looks at exacerbation triggers; and the third discusses the treatment and prevention of exacerbations using pharmacological and non-pharmacological interventions. The book’s structure allows comparisons between the definitions, short- and long-term consequences, triggers and therapeutic management of different respiratory diseases. It serves as a complete reference that raises awareness about the importance of acute exacerbations in patients with chronic lung diseases.
The coexistence of lung disease and cancer in the same person is a frequent occurrence. Evidence suggests that this coexistence sometimes goes beyond chance; in fact, both disease types are associated and the presence of one can be a risk factor or a protective factor for the other. In this Monograph, the Guest Editors bring together renowned clinical and scientific experts to provide an exhaustive review of the bidirectional relationship between respiratory diseases and cancer (not just lung cancer). The chapters: explore the common causal pathways of cancer and lung disease; consider the diseases from an epidemiological, clinical and therapeutic point of view; and discuss the many ways in which they interact to influence patient management. The result is a book that will generate a better understanding of this relationship, giving rise to a greater awareness of the possible development of lung disease in people with cancer, and of the different types of cancer that are frequently seen in those with lung diseases.