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The Neocortex
Experts review the latest research on the neocortex and consider potential directions for future research. Over the past decade, technological advances have dramatically increased information on the structural and functional organization of the brain, especially the cerebral cortex. This explosion of data has radically expanded our ability to characterize neural circuits and intervene at increasingly higher resolutions, but it is unclear how this has informed our understanding of underlying mechanisms and processes. In search of a conceptual framework to guide future research, leading researchers address in this volume the evolution and ontogenetic development of cortical structures, the cor...
Criticality as a signature of healthy neural systems: multi-scale experimental and computational studies
Since 2003, when spontaneous activity in cortical slices was first found to follow scale-free statistical distributions in size and duration, increasing experimental evidences and theoretical models have been reported in the literature supporting the emergence of evidence of scale invariance in the cortex. Although strongly debated, such results refer to many different in vitro and in vivo preparations (awake monkeys, anesthetized rats and cats, in vitro slices and dissociated cultures), suggesting that power law distributions and scale free correlations are a very general and robust feature of cortical activity that has been conserved across species as specific substrate for information sto...
Home Waters
“Beautiful. ... A lyrical companion to his father’s classic, A River Runs through It, chronicling their family’s history and bond with Montana’s Blackfoot River.” —Washington Post A "poetic" and "captivating" (Publishers Weekly) memoir about the power of place to shape generations, Home Waters is John N. Maclean's remarkable chronicle of his family's century-long love affair with Montana's majestic Blackfoot River, the setting for his father's classic novella, A River Runs through It. Maclean returns annually to the simple family cabin that his grandfather built by hand, still in search of the trout of a lifetime. When he hooks it at last, decades of longing promise to be fulfill...
Secrets of Creativity
Secrets of Creativity combines insights from an interdisciplinary group of experts to reveal the secrets of creativity that emerge from our everyday lives, and from the minds of exceptional individuals and their discoveries. Neuroscientists describe the functioning of the brain in creative acts of scientific discovery or artistic production. Humanists describe the workings of the creative mind in the composition of literary works and in works of art and music. Creativity is explored with respect to forms of intelligence, modes of experience, emotions, memory, and the interplay between the brain's nonconscious and conscious system activities.
Quantitative analysis of neuroanatomy
The true revolution in the age of digital neuroanatomy is the ability to extensively quantify anatomical structures and thus investigate structure-function relationships in great detail. Large-scale projects were recently launched with the aim of providing infrastructure for brain simulations. These projects will increase the need for a precise understanding of brain structure, e.g., through statistical analysis and models. From articles in this Research Topic, we identify three main themes that clearly illustrate how new quantitative approaches are helping advance our understanding of neural structure and function. First, new approaches to reconstruct neurons and circuits from empirical dat...
Picking Up the Slack
Canada has over-promised and under-delivered on climate change, setting weak goals and allowing carve-outs, exceptions, and exemptions to undermine its climate policies. Why, in an era when climate change is front of mind for so many people, have we failed to make progress? This question has been the source of heated debate across the political spectrum. In Picking Up the Slack, Andrew Green draws together different perspectives on the challenge facing Canada to offer an accessible account of the ideas and institutions that have impeded climate change action. Picking Up the Slack embraces the complexity of the problem, showing that its sources lie deep in Canada’s institutional arrangement...
Changing Actors in International Law
Changing Actors in International Law explores actors other than the ‘state’ in international law with a particular focus on under-researched actors or others that do not easily fit the category of a non-state actor (such as quasi-states, trans-government networks, Indigenous Peoples and self-determination claimant groups). It also examines less well studied aspects of otherwise well-researched actors such as individuals, corporations, NGOs and armed organised groups. In Part 1 of this book, authors examine the role and consequences of the participation of those actors in the process of international law creation. In Part 2, authors focus on the extent to which these actors can be held responsible under international law for its breach and their participation in traditional and non-traditional dispute resolution processes.
Computational Neuroscience: Theoretical Insights into Brain Function
Computational neuroscience is a relatively new but rapidly expanding area of research which is becoming increasingly influential in shaping the way scientists think about the brain. Computational approaches have been applied at all levels of analysis, from detailed models of single-channel function, transmembrane currents, single-cell electrical activity, and neural signaling to broad theories of sensory perception, memory, and cognition. This book provides a snapshot of this exciting new field by bringing together chapters on a diversity of topics from some of its most important contributors. This includes chapters on neural coding in single cells, in small networks, and across the entire c...
