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Extensively revised and updated, the new edition of the highly regarded Handbook of Proteolytic Enzymes is an essential reference for biochemists, biotechnologists and molecular biologists. Edited by world-renowned experts in the field, this comprehensive work provides detailed information on all known proteolytic enzymes to date. This two-volume set unveils new developments on proteolytic enzymes which are being investigatedin pharmaceutical research for such diseases as HIV, Hepatitis C, and the common cold. Volume I covers aspartic and metallo petidases while Volume II examines peptidases of cysteine, serine, threonine and unknown catalytic type. A CD-ROM accompanies the book containing f...
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The author of the bestseller White Mischief tells the story of the beautiful Langhorne sisters, who lived at the Pinnacle of high and powerful society from the end of the Civil War through the Second World War. Making their way across two continents, they left in their wakes rich husbands, fame, adoration, and scandal. Lizzie, Irene, Nancy, Phyllis, and Nora were born in Virginia to a family impoverished by the Civil War. Their father remade his fortune by collaborating with the Yankees and building rail-roads; the sisters became southern belles and northern debutantes. James Fox draws on unpublished correspondence between the sisters and their husbands, lovers, children, and the powerful an...
‘A lovely little book ... quietly lyrical, often funny and gently persuasive’ Sunday Times ‘Succinct, clear, sophisticated. I couldn't stop reading it’ Jeff VanderMeer
"The fox knows many things, but the hedgehog knows one big thing." This ancient Greek aphorism, preserved in a fragment from the poet Archilochus, describes the central thesis of Isaiah Berlin's masterly essay on Leo Tolstoy and the philosophy of history, the subject of the epilogue to War and Peace. Although there have been many interpretations of the adage, Berlin uses it to mark a fundamental distinction between human beings who are fascinated by the infinite variety of things and those who relate everything to a central, all-embracing system. Applied to Tolstoy, the saying illuminates a paradox that helps explain his philosophy of history: Tolstoy was a fox, but believed in being a hedge...
From Sean Connery to Roy Rogers, from comedy to political satire, films that include espionage as a plot device run the gamut of actors and styles. More than just "spy movies," espionage films have evolved over the history of cinema and American culture, from stereotypical foreign spy themes, to patriotic star features, to the Cold War plotlines of the sixties, and most recently to the sexy, slick films of the nineties. This filmography comprehensively catalogs movies involving elements of espionage. Each entry includes release date, running time, alternate titles, cast and crew, a brief synopsis, and commentary. An introduction analyzes the development of these films and their reflection of the changing culture that spawned them.
Includes Whittier's poetry, historical dates and birthdates of various literary and historical figures.
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