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The Ischemic Penumbra
The Ischemic Penumbra presents the current status of concepts and research on this topic and identifies the latest methods for clinicians to quickly and efficiently recognize viable cerebral tissue for enhanced stroke management. Focusing on state-of-the-science technologies and current trends, the book examines imaging strategies utilizing PET, SP
Embedded System Applications
Embedded systems encompass a variety of hardware and software components which perform specific functions in host systems, for example, satellites, washing machines, hand-held telephones and automobiles. Embedded systems have become increasingly digital with a non-digital periphery (analog power) and therefore, both hardware and software codesign are relevant. The vast majority of computers manufactured are used in such systems. They are called `embedded' to distinguish them from standard mainframes, workstations, and PCs. Athough the design of embedded systems has been used in industrial practice for decades, the systematic design of such systems has only recently gained increased attention...
Neurological Complications of Systemic Cancer and Antineoplastic Therapy
Neurological Complications of Systematic Cancer and Antineoplastic Therapy provides an in-depth review of common manifestations related to neurology that occur in patients with systemic cancer. These include brain metastases, spinal cord compression, cerebrovascular events, and leptomeningeal disease. The book also discusses less common complicatio
Machine learning in data analysis for stroke/endovascular therapy
With an estimated global incidence of 11 million patients per year, research involving ischemic stroke requires the collection and analysis of massive data sets affected by innumerable variables. Landmark studies that have historically shaped the foundation of our understanding of ischemic stroke and the development of management protocols have been derived from only a miniscule fraction of a percent of the entire population due to feasibility and capability. Machine learning provides an opportunity to capture data from an extraordinarily larger cohort size, which can be applied to training models to formulate algorithms to forecast outcomes with unparalleled accuracy and efficiency. The par...
Mental Practice: Clinical and Experimental Research in Imagery and Action Observation
There is now strong evidence demonstrating that the brain simulates action and other functions. Such action simulation can be evoked through conscious mental rehearsal of movement or imagery, but also through passive action observation watching movements in others. Furthermore, there is evidence to suggest that mental rehearsal of movement, or mental practice, can produce improvements normally attributed to practising actual movements. It is currently assumed that such improvements are due to neural activation associated with action simulation. However the neuroscience of mental practice efficacy is still poorly understood. The aim of this research topic is to clarify the underlying mechanis...
Stroke
The manuscripts in this book were generated from a conference occurring at the University of Heidelberg in September 1996. These manuscripts have been reviewed and updated by the designated authors in late 1997 for publication in early 1998. Conferences occur for a variety of reasons. These include the need to exchange information where complex activities are undergoing reassessment or change. For the emergency and critical care man agement of stroke this is certainly the situation. Today, both the pri mary care and the neurologic physician must provide medical care in an environment where daily change in the knowledge base of: brain function, disease mechanism(s), therapeutic efficacy, and ...
Brain Ischemia
Professor Caplan has extensively edited the book to shape and organize the contents into a succinct presentation by experts of the basic science and clinical aspects of the topic. The text has been divided into sections: The Brain.- Macroscopic and microscopic molecular aspects of brain ischemia, including pathophysiology, pathology, biochemistry, and clinical measurement.- Blood Vessels.- Their constitution and the pathology and physiology of the endothelium and arterial wall.- Blood Flow.- Its physics, control, rheology, and pathophysiology.- Blood.- The role of the cellular and serological constituents in coagulation and fibrinolysis. - Heart.- Sources of embolism and cardiac changes caused by brain ischemia.- And Epidemiology, Databases, and Trials. Prefatory remarks by Professor Caplan introduce each section. At the end of each section he relates the basic concepts to patient problems in the clinic, integrates the various contributions in the section, and covers other areas not discussed by the individual contributors.
