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The study of stem cell biology is under intensive investigations. Because stem cells have the unique capability to self-renew and differentiate into one or several cell types, they play a critical role in development, tissue homeostasis and regeneration. Stem cells also constitute promising cell candidates for cell therapy.The aim of this book is to provide an accurate knowledge on stem cell biology and regenerative medicine. This book will cover many topics in the field and is based on seminars given by recognized scientists involved the international master program on stem cell biology at the University Pierre and Marie Curie (UPMC) in Paris.
Is death inevitable? Until now, the history of mankind has been marked by this fatal fact. Religions, borders and progress are born from an ancient fear of death, comfort from this fear man often found only in religious paradigms. But according to José Luis Cordeiro and David Wood, the incontrovertible fact of death is no longer an absolute certainty - science and technology are preparing to tear down the final frontier: that of immortality. This accessible book provides insight into recent exponential advances in artificial intelligence, tissue regeneration, stem cell treatment, organ printing, cryopreservation, and genetic therapies that, for the first time in human history, offer a reali...
In this second volume in the series exploring Tumor Dormancy, Quiescence, and Cellular Senescence, discussion is focused on the role of tumor dormancy in diseases such as breast cancer, melanoma, prostate cancer, liver cancer and lung cancer. M. A. Hayat, the series editor, writes in the preface that little is known of factors regulating the transition of residual cancer into a dormant state or the subsequent reinitiation of growth. A majority of us, he says, have in situ tumors that may remain dormant or may progress into a lethal form of cancer; the former are prevented from recruiting their own blood supply. Section I covers Molecular Mechanisms, with chapters on the role of NAE inhibitor...
Dr. David Winters’ intellect is the greatest the modern world has ever known. He snatched fully functioning nanites right off the pages of science fiction and made them a reality. His latest discovery, however, will make the nanites pale in comparison, and he’s going to give this one to the world. With its impact on people and on the Earth itself so significant, however, will Winters’ latest discovery lead to an incredible new beginning for humanity, or will it usher in its downfall?
This book considers the branch of heredity known as "epigenetics" and its implications for a variety of diseases in humans and animals. After background information on the growth in understanding genetics and the mechanisms of the epigenetic control of gene expression, the book moves into its main focus: the gathering body of evidence connecting genetics to a range of significant illnesses, including cancer, autism, Alzheimer's disease, diabetes and others. Areas of uncertainty are stressed as well as the scientific debate concerning the role of environmental factors. The final chapters discuss the implications for society. Extensive notes provide additional details and personal anecdotes.
Volume 70 begins with two "Foundations in Cancer Research" articles, a staple of the Advances in Cancer Research series. The first article by Michael Stoker presents a review of some of the early advances made by cancer cell biology researchers. The second article by Emmanuel Farber describes the methods by which researchers delineate the phenotype of cells and ways to alter these phenotypes to prevent or delay carcinomas. Chidambaram and Dean illustrate the tumors and associated malformations of nevoid basal cell carcinoma. Koli and Keski-Oja review the effects of how transforming growth factor-b regulates cell proliferation, differentiation, and morphogenesis and its regulation by the ster...
Top researchers in the field introduce interdisciplinary perspectives on senescence, presenting new insights and cutting-edge research.
In the early 21st century, the advances of science, followed by technology, have been very impressive and opened up hither to unthought-of prospects in every domain. Scientific 'Previsionists' believe it will lay the foundation for deep changes in the human being. This is in no way a matter of science fiction but rather rational and foreseeable extrapolations of many recent results in various scientific fields. Will Man become a mutating GMO, a humanoid robot, a hybrid of both? Will his life be extended much longer or even indefinitely? Will he reproduce in vitro in the near future? These are questions we should begin to ask now, for our children will likely experience these changes, but our grandchildren will live in a quite different world.
"A history of the deep social and economic changes of France, told through the story of a single extended family, from the mid-eighteenth through the early twentieth century"--