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Vitamins and Hormones
Recent developments in research on diabetes mellitus embrace basic disciplines such as physiology, biochemistry, morphology and evolving sub-specialities. Fundamental studies on the heterogeneous diabetic syndrome are oriented towards regulatory principles of cell metabolism, genetic control mechanisms of insulin biosynthesis and secretion, as well as autoimmune events implicated in selective destruction of pancreatic ß-cell. In parallel, efforts are made for a better understanding of normal versus impaired biological actions, both of insulin and insulin-like growth factor I, and the translocation process of glucose transporters in insulin-responsive target cells.
The Structure and Metabolism of the Pancreatic Islets: A Centennial of Paul Langerhans' Discovery is a collection of that presents the advancement in the field of pancreatic islet research, particularly in the area of biosynthesis and secretion of insulin. The title also serves as a commemorative material to Paul Langerhans' work. The text first covers the differentiation and growth of the endocrine pancreas, and then proceeds to tackling a- and ß-cells. Next, the selection deals with the glucose metabolism of the pancreatic islets. The text also discusses the biosynthesis and storage of insul ...
The Structure and Metabolism of the Pancreatic Islets: A Centennial of Paul Langerhans' Discovery is a collection of that presents the advancement in the field of pancreatic islet research, particularly in the area of biosynthesis and secretion of insulin. The title also serves as a commemorative material to Paul Langerhans' work. The text first covers the differentiation and growth of the endocrine pancreas, and then proceeds to tackling a- and ß-cells. Next, the selection deals with the glucose metabolism of the pancreatic islets. The text also discusses the biosynthesis and storage of insulin, along with insulin release. The seventh part details pancreatic islets and diabetes. The book will be of great use to students, researchers, and practitioners of medicine.
An enormous amount of research effort has been directed toward elucidating the mechanism by which substances are extruded from cells; and reviews have been written and symposia held in order to systematize the plethora of evidence made available. However, the approaches employed to study the secretory process have been so diverse that it is difficult, if not impossible, for one individual or even a group of individuals to keep abreast of all aspects of the field and to analyze them critically. Thus I undertook the writing of this volume with a great deal of trepidation. In searching for some starting point, I naturally considered as my primary focus the role of calcium in the secretory proce...
« Un parcours ça ne se fait jamais seul. Le talent, le travail et la chance, ça ne suffit pas. Il faut être accompagné par les bonnes personnes et depuis mes débuts, j'ai eu la chance de l'être. Le travail, le talent, la chance et les bonnes personnes, ça ne suffit pas non plus si on n'est pas élu par les autres, si on n'est pas élu par les gens qui vous regardent, qui vous aiment et qui aiment vos chansons et par cette personne qui est à la fois multiple et unique qui s'appelle le public. » (Victoires de la Musique, 2018). C'est de cette « personne à la fois multiple et unique » dont il est question dans ce livre : les fans d'Étienne Daho. Certains l'appellent familièrement...
Cyclic AMP provides information pertinent to cyclic adenosine 3',5'-monophosphate (AMP), a regulatory agent that controls the rate of a number of cellular processes. This book discusses the heat-stable factor mediating the action of glucagon and epinephrine on the activation of liver phosphorylase. Organized into 12 chapters, this book starts with an overview of the biological role of cyclic AMP, which is extended from a relatively simple role in liver glycogenolysis to a significant regulatory agent in most mammalian tissues. This text then discusses the development that led to the discovery of the heat-stable factor from investigations with cyclic nucleotides. Other chapters explore the chemical agents, which are released from one group of cells and travel via the bloodstream to affect one or more different groups of cells. The final chapter discusses the role of cyclic AMP to mammalian physiology, with emphasis on the many possible defects that may lead to human disease. This book is a valuable resource for graduate students and clinical investigators involved in biological and biomedical sciences.