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The history of whaling as an industry on this continent has been well-told in books, including some that have been bestsellers, but what hasn’t been told is the story of whaling’s leaders of color in an era when the only other option was slavery. Whaling was one of the first American industries to exhibit diversity. A man became a captain not because he was white or well connected, but because he knew how to kill a whale. Along the way, he could learn navigation and reading and writing. Whaling presented a tantalizing alternative to mainland life. Working with archival records at whaling museums, in libraries, from private archives and interviews with people whose ancestors were whaling ...
In an attempt to better account for the impressive diversity of positions and relations that characterizes the eighteenth-century world, this collection proposes a new methodological frame, one that is less hierarchical in approach and more focused, instead, on the nature of these interactions, on their Addisonian “usefulness,” declared goals, and (un)intended results. By shifting focus from a cultural-historicist approach to sociability to the rhizomatic nature of eighteenth-century associations, this collection approaches them through new methodological lenses that include social network analysis, assemblage and graph theory, social media and digital humanities scholarship. Imagining t...
This book discusses the latest developments in Poly (ADP-ribose) polymerase (PARP) inhibitor drug development. It focuses on the translational and clinical development of the latest drugs, as well as the evidence for regulatory approval of PARP inhibitors in multiple different molecular subtypes and tumor indications. The most-up-to-date information on basic scientific research on DNA repair pathways and the DNA Damage Response (DDR) is also covered. Every chapter contains insight into the preclinical, translational along with clinical aspects of a specific DDR inhibitor with key and expert opinion points reinforcing the most important concepts detailed to enable the reader to develop a deep understanding of the topic. Targeting the DNA Damage Response for Cancer Therapy comprehensively reviews the application of PARP and other DDR inhibitors across oncology disciplines. Therefore, it is a valuable resource for all medical professionals and researchers who use or who are researching the use of these inhibitors on a day-to-day basis.
As the meeting point between Europe, colonial America, and Africa, the history of the Atlantic world is a constantly shifting arena, but one which has been a focus of huge and vibrant debate for many years. In over thirty chapters, all written by experts in the field, The Atlantic World takes up these debates and gathers together key, original scholarship to provide an authoritative survey of this increasingly popular area of world history. The book takes a thematic approach to topics including exploration, migration and cultural encounters. In the first chapters, scholars examine the interactions between groups which converged in the Atlantic world, such as slaves, European migrants and Nat...
The history of the American city is, in many ways, the history of the United States. Although rural traditions have also left their impact on the country, cities and urban living have been vital components of America for centuries, and an understanding of the urban experience is essential to comprehending America’s past. America’s Urban History is an engaging and accessible overview of the life of American cities, from Native American settlements before the arrival of Europeans to the present-day landscape of suburban sprawl, urban renewal, and a heavily urbanized population. The book provides readers with a rich chronological and thematic narrative, covering themes including: The role of cities in the European settlement of North America Cities and westward expansion Social reform in the industrialized cities The impact of the New Deal The growth of the suburbs The relationships between urban forms and social issues of race, class, and gender Covering the evolving story of the American city with depth and insight, America's Urban History will be the first stop for all those seeking to explore the American urban experience.
As biosensors comprise a prospective alternative to traditional chemical analyses, enabling fast on- and in-line measurements with sufficient selectivity, the field is expanding rapidly and is offering new ideas and developments every day. This book aims to cover the present state of the art in the biosensor technology and introduce the general aspects of biosensor- based techniques and methods. The book consists of 13 chapters by 44 authors and is divided into 3 sections, focused on bio-recognition techniques, signal transduction methods and signal analysis.
Fear and the Shaping of Early American Societies is the first collection of essays to argue that fear permeated the colonial societies of 17th- and 18th-century America and to analyse its impact on the political decision-making processes from a variety of angles and locations. Indeed, the thirteen essays range from Canada to the Chesapeake, from New England to the Caribbean and from the Carolina Backcountry to Dutch Brazil. This volume assesses the typically American nature of fear factors and the responses they elicited in a transatlantic context. The essays further explore how the European colonists handled such challenges as Indian conspiracies, slave revolts, famine, “popery” and tyranny as well as werewolves and a dragon to build cohesive societies far from the metropolis. Contributors are: Sarah Barber, Benjamin Carp, Leslie Choquette, Anne-Claire Faucquez, Lauric Henneton, Elodie Peyrol-Kleiber, Susanne Lachenicht, Bertie Mandelblatt, Mark Meuwese, L. H. Roper, David L. Smith, Bertrand Van Ruymbeke, Christopher Vernon, and David Voorhees.
This book presents the latest advances in ultrafast science, including ultrafast laser and measurement technology, and studies of ultrafast phenomena. It summarizes the results presented at the 12th Ultrafast Phenomena Conference and reviews the state of the art of this important and rapidly advancing field.
Chemical Vapor Deposition Polymerization - The Growth and Properties of Parylene Thin Films is intended to be valuable to both users and researchers of parylene thin films. It should be particularly useful for those setting up and characterizing their first research deposition system. It provides a good picture of the deposition process and equipment, as well as information on system-to-system variations that is important to consider when designing a deposition system or making modifications to an existing one. Also included are methods to characterizae a deposition system's pumping properties as well as monitor the deposition process via mass spectrometry. There are many references that will lead the reader to further information on the topic being discussed. This text should serve as a useful reference source and handbook for scientists and engineers interested in depositing high quality parylene thin films.
New and unpublished U.S. and international research on multifunctional, active, biobased, SHM, self-healing composites -- from nanolevel to large structures New information on modeling, design, computational engineering, manufacturing, testing Applications to aircraft, bridges, concrete, medicine, body armor, wind energy This fully searchable CD-ROM contains 135 original research papers on all phases of composite materials. The document provides cutting edge research by US, Canadian, and Japanese authorities on matrix-based and fiber composites from design to damage analysis and detection. Major divisions of the work include: Structural Health Monitoring, Multifunctional Composites, Integrated Computational Materials Engineering, Interlaminar Testing, Analysis-Shell Structures, Thermoplastic Matrices, Analysis Non-classical Laminates, Bio-Based Composites, Electrical Properties, Dynamic Behavior, Damage/Failure, Compression-Testing, Active Composites, 3D Reinforcement, Dielectric Nanocomposites, Micromechanical Analysis, Processing, CM Reinforcement for Concrete, Environmental Effects, Phase-Transforming, Molecular Modeling, Impact.