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Sleeping With The Enemy They hide in mattresses. They wait till you're asleep. They rise in the dead of night to feast on your blood. They can multiply by the hundreds in less than a week. They are one of the most loathsome, hellish species to ever grace God's green earth. Thought to be eradicated decades ago, thanks to global travel they're back. And with them comes a nightmare beyond imagining. Bed bugs. Infected with a plague virus so deadly it makes Ebola look like a summer cold. One bite turns people into homicidal maniacs. Now they're in Chicago. And migrating to all points north, south, east, and west. The rest of the world is already itching. The U.S. government and the CDC are helpless to stop it. Only one man knows what's causing the epidemic. And the powers-that-be want him dead. "A fresh new talent with an amazing ability to astonish." --David Morrell, bestselling author of First Blood
The Last Roll is a first-person depiction of a cancer patient's changing perspectives on life, death, art and the world.
Operative Techniques in Sports Medicine Surgery provides full-color, step-by-step explanations of all operative procedures in sports medicine. It contains the sports-related chapters from Sam W. Wiesel's Operative Techniques in Orthopaedic Surgery. Written by experts from leading institutions around the world, this superbly illustrated volume focuses on mastery of operative techniques and also provides a thorough understanding of how to select the best procedure, how to avoid complications, and what outcomes to expect. The user-friendly format is ideal for quick preoperative review of the steps of a procedure. Each procedure is broken down step by step, with full-color intraoperative photogr...
Diagnosis and Treatment of Human Mycoses brings together globally-recognized mycoses experts to guide readers in the use of current knowledge in the field of medical mycology to manage those who suffer from fungal infections (mycoses). Often, diagnostic strategies and tests, including basic and directed culturing techniques, histopathology with standard and special stains, serological methods, and radiological studies all need to be considered and commonly combined to make the diagnosis of fungal infection. This volume first introduces and reviews these tools separately and then as they pertain to specific infections or groups of diseases. The volume consists of four parts. Parts I-III provide an overview of diagnostic and therapeutic tools, and part IV presents the human mycoses. Diagnosis and Treatment of Human Mycoses is meant to be a concise text that will provide the busy infectious disease, hematology–oncology, pulmonology, or critical care specialist a practical tool to diagnose and manage fungal infections. In addition, the depth of the material in the text will provide these and other medical specialists and trainees an excellent reference and learning resource.
In 2003, the President’s budget for bioterrorism defense totalled more than $5 billion. Today, the nation’s top academic scientists are scrambling to begin work to understand Bacillus anthracis and develop new vaccines and drugs. However, just five years ago, only the US Department of Defense (DOD) seemed concerned about these “exotic” agents. In 1997, the DOD spent approximately $137 million on biodefense to protect the deployed force, while academe, industry, local governments, and most of our federal leadership was oblivious to, and in some cases doubtful of, the seriousness of the threat. The National Institutes of Health (NIH) received the largest budget increase in the organization’s history. Fortunately, during this time of national urgency, a sound base exists on which to build our defenses against this new threat. A relatively small cadre of dedicated scientists within the US Army Medical Research and Materiel Command (USAMRMC) laid this foundation over the past 20 years.
Operative Techniques in Orthopaedic Surgery is the first major new comprehensive text and reference on surgical techniques in orthopaedics. Written by over 800 experts from leading institutions around the world, this superbly illustrated four-volume reference focuses on mastery of operative techniques and also provides a thorough understanding of how to select the best procedure, how to avoid complications, and what outcomes to expect. The user-friendly format is ideal for quick preoperative review of the steps of a procedure. Each procedure is broken down step by step, with full-color intraoperative photographs and drawings that demonstrate how to perform each technique. Extensive use of bu...
This book serves as a practical guide to managing some of the most difficult infection problems with multiple drug-resistant organisms. The authors cover all classes of microbial infections from gram-positive bacteria to mycobacteria to viral infections and provide everything from the epidemiological and scientific background to the management of the multiple drug-resistant infections in both major hospital and community-acquired pathogens, making this an essential reference for all infectious disease practitioners.
The concept of innate immunity refers to the first-line host defense that serves to limit infection in the early hours after exposure to microorganisms. Recent data have highlighted similarities between pathogen recognition, signaling pathways, and effector mechanisms of innate immunity in Drosophila and mammals, pointing to a common ancestry of these defenses. In addition to its role in the early phase of defense, innate immunity in mammals appears to playa key role in stimulating the subsequent clonal response of adaptive immunity. Recent exciting information has determined that the templates that are laid down in primitive life forms, like flowering plants and insects, form the basic prin...
A cutting-edge review of the major research areas of adjuvant discovery, design, development, and use. The authors lay down a rational basis for vaccine adjuvant function and analyze a number of significantly distinct adjuvant-active molecules to illuminate the principles of their function and use. The focus is on specific receptor-ligand interactions, including the molecular features needed for a compound to possess adjuvant activity. The critical interface zone between the innate and adaptive immune systems is also analyzed to show how adjuvants exert their effects on T- and B-cell activation. Additional chapters address the possibility of tailoring adjuvants to yield optimally safe and effective responses.
In this second edition of Infectious Diseases and Arthropods, Jerome Goddard summarizes the latest thinking about the biological, entomological, and clinical aspects of the major vector-borne diseases around the world. His book covers mosquito-, tick-, and flea-borne diseases, and a variety of other miscellaneous vector-borne diseases, including Chagas' disease, African sleeping sickness, onchocerciasis, scrub typhus, and louse-borne infections. The author provides for each disease a description of the vector involved, notes on its biology and ecology, distribution maps, and general clinical guidelines for treatment and control. Among the diseases fully discussed are malaria, dengue and yell...