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Workflow-based Process Controlling Systems provide companies with the ability to measure the operational performance of their business processes in a timely and accurate fashion. The combination of workflow audit trails with data warehouse technology and operational business data allows for complex analyses that can support managers in their assessment of an organization's performance. The increasing maturity of business process management and data warehouse systems enables the design and development of advanced process-oriented management information systems. Michael zur Muehlen discusses the integration of workflow audit trail data with existing data warehouse structures and develops a ref...
Development of an effective anticancer therapeutic necessitates the selection of cancer-related or cancer-specific pathways or molecules that are sensitive to intervention. Several such critical yet sensitive molecular targets have been recognized, and their specific antagonists or inhibitors validated as potential therapeutics in preclinical models. Yet, majority of anticancer principles or therapeutics show limited success in the clinical translation. Thus, the need for the development of an effective therapeutic strategy persists.
“Altered energy metabolism” in cancer is one of the earliest known biochemical phenotypes which dates back to the early 20th century. The German ...
InfoWorld is targeted to Senior IT professionals. Content is segmented into Channels and Topic Centers. InfoWorld also celebrates people, companies, and projects.
Recent rapid advancement in machine learning (ML) technologies have unlocked the potential for realizing advanced vehicle functions that were previously not feasible using traditional approaches to software development. One prominent example is the area of automated driving. However, there is much discussion regarding whether ML-based vehicle functions can be engineered to be acceptably safe, with concerns related to the inherent difficulty and ambiguity of the tasks to which the technology is applied. This leads to challenges in defining adequately safe responses for all possible situations and an acceptable level of residual risk, which is then compounded by the reliance on training data. ...
The editors bring two terms, narrative and innovation, together in an interdisciplinary and interactive way. Narratives are ubiquitous and hold the potential to indicate future changes in politics, economies and markets. As “stressors” and stabilizers in organizations, narratives and changes in the consensus narrative indicate the need for strategic change or organizational stasis and may be utilized as a source for early recognition in strategic management. The use of narratives in management, however, makes it necessary to adopt a new perspective. This volume offers a polyphonic forum for the development of an interpretive approach towards business administration, strategic management, and entrepreneurship, by introducing instruments of semiotics, linguistics, narratology, and others. This compilation, therefore, presents a comprehensive overview of scientific and industrial perspectives beyond the mainstream.
This volume addresses the emerging area of human computation, The chapters, written by leading international researchers, explore existing and future opportunities to combine the respective strengths of both humans and machines in order to create powerful problem-solving capabilities. The book bridges scientific communities, capturing and integrating the unique perspective and achievements of each. It coalesces contributions from industry and across related disciplines in order to motivate, define, and anticipate the future of this exciting new frontier in science and cultural evolution. Readers can expect to find valuable contributions covering Foundations; Application Domains; Techniques and Modalities; Infrastructure and Architecture; Algorithms; Participation; Analysis; Policy and Security and the Impact of Human Computation. Researchers and professionals will find the Handbook of Human Computation a valuable reference tool. The breadth of content also provides a thorough foundation for students of the field.
Pulitzer Prize–winning author David J. Garrow’s stirring and essential history of the politics of abortion and America’s battle for the right to choose In 1973, the Supreme Court handed down its landmark Roe v. Wade decision legalizing abortion, and more than forty years later the issue continues to spark controversy and divisiveness. But behind this historic legal case lie the battles women fought to establish their rights to use contraceptives and choose to have an abortion. Liberty and Sexuality traces these political and legal struggles in the decades leading up to Roe v. Wade—including the momentous 1965 Supreme Court ruling in Griswold v. Connecticut that established a constitu...